Transcriptional regulation of Notch1 by nuclear factor-κB during T cell activation

Abstract Notch1 plays important roles in T cell development and is highly expressed in activated CD4+ T cells. However, the underlying mechanism of Notch1 transcription in T cells has not been fully characterized. Therefore, we aimed to determine how Notch1 expression is regulated during the activat...

Полное описание

Библиографические подробности
Главные авторы: Jeong-Ryul Hwang, Donghwan Kim, Jung-Ah Kang, Sang-Heon Park, Sung-Gyoo Park
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2023-01-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-022-26674-1