Current status of antigen-specific T-cell immunotherapy for advanced renal-cell carcinoma

Current status of antigen-specific T-cell immunotherapy for advanced renal-cell carcinoma

In renal-cell carcinoma (RCC), tumor-reactive T-cell responses can occur spontaneously or in response to systemic immunotherapy with cytokines and immune checkpoint inhibitors. Cancer vaccines and engineered T-cell therapies are designed to selectively augment tumor antigen-specific CD8+ T-cell resp...

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Bibliographic Details
Main Authors: Yuexin Xu, Chris P. Miller, Edus H. Warren, Scott S. Tykodi
Format: Article
Language:English
Published: Taylor & Francis Group 2021-07-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
renal cell carcinoma
tumor-infiltrating t cell
tumor antigen
t cell receptor
cancer vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2020.1870846

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