Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates

Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates

Protein modification with non-canonical amino acids (ncAAs) represents a useful technology to afford homogenous samples of bioconjugates with site-specific modification. This technique can be directly applied to the detection of aberrant SUMOylation patterns, which are often indicative of disease st...

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Bibliographic Details
Main Authors: Alexander C. Williard, Hannah J. Switzer, Christina A. Howard, Rui Yin, Brent L. Russell, Ritwik Sanyal, Shaun Yu, Trinity M. Myers, Brian M. Flood, Oliver Kerscher, Douglas D. Young
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
bioconjugates
non-canonical amino acids
SUMO
protein modification
Online Access:https://www.mdpi.com/1999-4923/14/12/2826

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