Cytokines and HIF-1α as dysregulation factors of migration and differentiation of monocyte progenitor cells of endotheliocytes in the pathogenesis of ischemic cardiomyopathy

Cytokines and HIF-1α as dysregulation factors of migration and differentiation of monocyte progenitor cells of endotheliocytes in the pathogenesis of ischemic cardiomyopathy

Background. Angiogenic endothelial dysfunction and progenitor endothelial cells (EPCs) in ischemic cardiomyopathy (ICMP) have not been studied enough.The aim. To establish the nature of changes in the cytokine profile and HIF-1α in blood and bone marrow associated with impaired differentiation of mo...

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Bibliographic Details
Main Authors: O. A. Denisenko, S. P. Chumakova, O. I. Urazova, V. M. Shipulin, A. S. Pryakhin
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2022-12-01
Series:Acta Biomedica Scientifica
Subjects:
cytokines
ischemic cardiomyopathy
coronary heart disease
progenitor endothelial cells
hypoxia-inducible factor
bone marrow
Online Access:https://www.actabiomedica.ru/jour/article/view/3822

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