Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia
Objectives: Diabetes mellitus (DM) patients are considered to be at high risk for contracting latent tuberculosis infection (LTBI). This study aimed to determine the prevalence of LTBI and its associated factors among diabetic patients attending primary care clinics in Terengganu state, Malaysia. Me...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oman Medical Specialty Board
2023-09-01
|
| Series: | Oman Medical Journal |
| Subjects: | |
| Online Access: | https://omjournal.org/articleDetails.aspx?coType=1&aId=3568 |
| _version_ | 1827380446510448640 |
|---|---|
| author | Nur Fatini Husain Harmy Mohamed Yusoff Nurulhuda Mat Hassan Aniza Abdul Aziz |
| author_facet | Nur Fatini Husain Harmy Mohamed Yusoff Nurulhuda Mat Hassan Aniza Abdul Aziz |
| author_sort | Nur Fatini Husain |
| collection | DOAJ |
| description | Objectives: Diabetes mellitus (DM) patients are considered to be at high risk for contracting latent tuberculosis infection (LTBI). This study aimed to determine the prevalence of LTBI and its associated factors among diabetic patients attending primary care clinics in Terengganu state, Malaysia. Methods: This cross-sectional study was conducted among diabetic patients attending 11 health clinics in the Terengganu region from June 2017 to November 2018. The selected participants were administered a tuberculin skin test (TST). Simple and multivariate logistic regressions were applied to evaluate the significant associated factors of LTBI. Results: The total number of participants were 703 DM patients. The factors found associated with LTBI were poor diabetic control status (odds ratio (OR) = 8.53; p=0.008), being a healthcare worker (OR = 7.91; p=0.001), history of contact with TB patients (OR = 5.69; p < 0.001), bronchial asthma (OR = 5.28; p=0.019), coronary heart disease (OR = 3.45; p=0.026), and nephropathy (OR = 0.34; p=0.040). The presence of LTBI was found in 34 (4.8%) participants. Conclusions: At 4.8%, the prevalence of LTBI among DM patients in Terengganu is relatively low. Diabetics with poorly controlled blood glucose levels, nephropathy, bronchial asthma, coronary heart disease, history of TB patient contact, or working in the healthcare profession should be periodically tested for LTBI. |
| first_indexed | 2024-03-08T13:33:00Z |
| format | Article |
| id | doaj.art-fdf07cb72eb04429996b2da55d3f3395 |
| institution | Directory Open Access Journal |
| issn | 1999-768X 2070-5204 |
| language | English |
| last_indexed | 2024-03-08T13:33:00Z |
| publishDate | 2023-09-01 |
| publisher | Oman Medical Specialty Board |
| record_format | Article |
| series | Oman Medical Journal |
| spelling | doaj.art-fdf07cb72eb04429996b2da55d3f33952024-01-17T05:23:27ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042023-09-01385e546e54610.5001/omj.2023.97Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, MalaysiaNur Fatini Husain0Harmy Mohamed Yusoff1Nurulhuda Mat Hassan2Aniza Abdul Aziz3Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, MalaysiaFaculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, MalaysiaFaculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, MalaysiaFaculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, MalaysiaObjectives: Diabetes mellitus (DM) patients are considered to be at high risk for contracting latent tuberculosis infection (LTBI). This study aimed to determine the prevalence of LTBI and its associated factors among diabetic patients attending primary care clinics in Terengganu state, Malaysia. Methods: This cross-sectional study was conducted among diabetic patients attending 11 health clinics in the Terengganu region from June 2017 to November 2018. The selected participants were administered a tuberculin skin test (TST). Simple and multivariate logistic regressions were applied to evaluate the significant associated factors of LTBI. Results: The total number of participants were 703 DM patients. The factors found associated with LTBI were poor diabetic control status (odds ratio (OR) = 8.53; p=0.008), being a healthcare worker (OR = 7.91; p=0.001), history of contact with TB patients (OR = 5.69; p < 0.001), bronchial asthma (OR = 5.28; p=0.019), coronary heart disease (OR = 3.45; p=0.026), and nephropathy (OR = 0.34; p=0.040). The presence of LTBI was found in 34 (4.8%) participants. Conclusions: At 4.8%, the prevalence of LTBI among DM patients in Terengganu is relatively low. Diabetics with poorly controlled blood glucose levels, nephropathy, bronchial asthma, coronary heart disease, history of TB patient contact, or working in the healthcare profession should be periodically tested for LTBI.https://omjournal.org/articleDetails.aspx?coType=1&aId=3568latent tuberculosis infectiontuberculin testdiabetes mellitusprevalencemalaysia |
| spellingShingle | Nur Fatini Husain Harmy Mohamed Yusoff Nurulhuda Mat Hassan Aniza Abdul Aziz Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia Oman Medical Journal latent tuberculosis infection tuberculin test diabetes mellitus prevalence malaysia |
| title | Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia |
| title_full | Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia |
| title_fullStr | Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia |
| title_full_unstemmed | Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia |
| title_short | Prevalence of Latent Tuberculosis Infection and its Associated Factors Among Diabetic Patients Availing Primary Health Care in Terengganu State, Malaysia |
| title_sort | prevalence of latent tuberculosis infection and its associated factors among diabetic patients availing primary health care in terengganu state malaysia |
| topic | latent tuberculosis infection tuberculin test diabetes mellitus prevalence malaysia |
| url | https://omjournal.org/articleDetails.aspx?coType=1&aId=3568 |
| work_keys_str_mv | AT nurfatinihusain prevalenceoflatenttuberculosisinfectionanditsassociatedfactorsamongdiabeticpatientsavailingprimaryhealthcareinterengganustatemalaysia AT harmymohamedyusoff prevalenceoflatenttuberculosisinfectionanditsassociatedfactorsamongdiabeticpatientsavailingprimaryhealthcareinterengganustatemalaysia AT nurulhudamathassan prevalenceoflatenttuberculosisinfectionanditsassociatedfactorsamongdiabeticpatientsavailingprimaryhealthcareinterengganustatemalaysia AT anizaabdulaziz prevalenceoflatenttuberculosisinfectionanditsassociatedfactorsamongdiabeticpatientsavailingprimaryhealthcareinterengganustatemalaysia |