Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

As a critical linker between mTORC1 and mTORC2, Akt is important for the cell metabolism. The role of Akt in the function and development of B and T cells is well characterized, however, the role of Akt for development and function of iNKT cells is unknown. iNKT cells bridge the adaptive and innate...

Full description

Bibliographic Details
Main Authors: LinLin Niu, Xingtian Xuan, Jinzhi Wang, Liling Li, Di Yang, Yukai Jing, Lisa S. Westerberg, Chaohong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Akt2
iNKT
ICOS
NKT17
FoxO-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01940/full

Similar Items

Similar Items