Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology
How soft tissues respond to mechanical load is essential to their biological function. Here, the authors discover that – contrary to predictions of poroelasticity – fluid mobility in collagenous tissues induces drastic volume decrease with tensile loading and pronounced chemo-mechanical coupling....
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-00801-3 |
| _version_ | 1818423216057614336 |
|---|---|
| author | Alexander E. Ehret Kevin Bircher Alberto Stracuzzi Vita Marina Manuel Zündel Edoardo Mazza |
| author_facet | Alexander E. Ehret Kevin Bircher Alberto Stracuzzi Vita Marina Manuel Zündel Edoardo Mazza |
| author_sort | Alexander E. Ehret |
| collection | DOAJ |
| description | How soft tissues respond to mechanical load is essential to their biological function. Here, the authors discover that – contrary to predictions of poroelasticity – fluid mobility in collagenous tissues induces drastic volume decrease with tensile loading and pronounced chemo-mechanical coupling. |
| first_indexed | 2024-12-14T13:38:37Z |
| format | Article |
| id | doaj.art-fdf292a5b743449e814b2058b755fd6b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T13:38:37Z |
| publishDate | 2017-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-fdf292a5b743449e814b2058b755fd6b2022-12-21T22:59:32ZengNature PortfolioNature Communications2041-17232017-10-018111010.1038/s41467-017-00801-3Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiologyAlexander E. Ehret0Kevin Bircher1Alberto Stracuzzi2Vita Marina3Manuel Zündel4Edoardo Mazza5ETH Zurich, Institute for Mechanical SystemsETH Zurich, Institute for Mechanical SystemsETH Zurich, Institute for Mechanical SystemsETH Zurich, Institute for Mechanical SystemsETH Zurich, Institute for Mechanical SystemsETH Zurich, Institute for Mechanical SystemsHow soft tissues respond to mechanical load is essential to their biological function. Here, the authors discover that – contrary to predictions of poroelasticity – fluid mobility in collagenous tissues induces drastic volume decrease with tensile loading and pronounced chemo-mechanical coupling.https://doi.org/10.1038/s41467-017-00801-3 |
| spellingShingle | Alexander E. Ehret Kevin Bircher Alberto Stracuzzi Vita Marina Manuel Zündel Edoardo Mazza Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology Nature Communications |
| title | Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| title_full | Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| title_fullStr | Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| title_full_unstemmed | Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| title_short | Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| title_sort | inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology |
| url | https://doi.org/10.1038/s41467-017-00801-3 |
| work_keys_str_mv | AT alexandereehret inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology AT kevinbircher inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology AT albertostracuzzi inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology AT vitamarina inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology AT manuelzundel inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology AT edoardomazza inverseporoelasticityasafundamentalmechanisminbiomechanicsandmechanobiology |