Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil
ABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. I...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pneumologia e Tisiologia
2019-04-01
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| Series: | Jornal Brasileiro de Pneumologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000200202&lng=en&tlng=en |
| _version_ | 1818520443229831168 |
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| author | Ursulla Vilella Andrade Sandra Maria do Valle Leone de Oliveira Marilene Rodrigues Chang Edy Firmina Pereira Ana Paula da Costa Marques Lidia Raquel de Carvalho Rinaldo Poncio Mendes Anamaria Mello Miranda Paniago |
| author_facet | Ursulla Vilella Andrade Sandra Maria do Valle Leone de Oliveira Marilene Rodrigues Chang Edy Firmina Pereira Ana Paula da Costa Marques Lidia Raquel de Carvalho Rinaldo Poncio Mendes Anamaria Mello Miranda Paniago |
| author_sort | Ursulla Vilella Andrade |
| collection | DOAJ |
| description | ABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment. Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p < 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604). Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy. |
| first_indexed | 2024-12-11T01:37:26Z |
| format | Article |
| id | doaj.art-fdf62b62261346debf082d5ff231a3df |
| institution | Directory Open Access Journal |
| issn | 1806-3756 |
| language | English |
| last_indexed | 2024-12-11T01:37:26Z |
| publishDate | 2019-04-01 |
| publisher | Sociedade Brasileira de Pneumologia e Tisiologia |
| record_format | Article |
| series | Jornal Brasileiro de Pneumologia |
| spelling | doaj.art-fdf62b62261346debf082d5ff231a3df2022-12-22T01:25:10ZengSociedade Brasileira de Pneumologia e TisiologiaJornal Brasileiro de Pneumologia1806-37562019-04-0145210.1590/1806-3713/e20180167S1806-37132019000200202Treatment compliance of patients with paracoccidioidomycosis in Central-West BrazilUrsulla Vilella AndradeSandra Maria do Valle Leone de OliveiraMarilene Rodrigues ChangEdy Firmina PereiraAna Paula da Costa MarquesLidia Raquel de CarvalhoRinaldo Poncio MendesAnamaria Mello Miranda PaniagoABSTRACT Objective: To evaluate the treatment compliance of patients with paracoccidioidomycosis. Methods: We studied 188 patients with paracoccidioidomycosis admitted to a tertiary referral hospital in the Central-West Region of Brazil from 2000 to 2010, to assess their compliance to treatment. In order to be considered compliant, patients needed to present two established criteria: (1) receive medicines from the pharmacy, and (2) achieve a self-reported utilization of at least 80% of the dispensed antifungal compounds prescribed since their previous appointment. Results: Most patients were male (95.7%), had the chronic form of the disease (94.2%), and were treated with cotrimoxazole (86.2%). Only 44.6% of patients were treatment compliant. The highest loss to follow-up was observed in the first 4 months of treatment (p < 0.02). Treatment compliance was higher for patients with than for those without pulmonary involvement (OR: 2.986; 95%CI 1.351-6.599), and higher for patients with than without tuberculosis as co-morbidity (OR: 2.763; 95%CI 1.004-7.604). Conclusions: Compliance to paracoccidioidomycosis treatment was low, and the period with the highest loss to follow-up corresponds to the first four months. Pulmonary paracoccidioidal involvement or tuberculosis comorbidity predicts a higher compliance to paracoccidioidomycosis therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000200202&lng=en&tlng=enParacoccidioidomycosisTreatment adherence and complianceloss to follow-upmycoses |
| spellingShingle | Ursulla Vilella Andrade Sandra Maria do Valle Leone de Oliveira Marilene Rodrigues Chang Edy Firmina Pereira Ana Paula da Costa Marques Lidia Raquel de Carvalho Rinaldo Poncio Mendes Anamaria Mello Miranda Paniago Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil Jornal Brasileiro de Pneumologia Paracoccidioidomycosis Treatment adherence and compliance loss to follow-up mycoses |
| title | Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil |
| title_full | Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil |
| title_fullStr | Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil |
| title_full_unstemmed | Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil |
| title_short | Treatment compliance of patients with paracoccidioidomycosis in Central-West Brazil |
| title_sort | treatment compliance of patients with paracoccidioidomycosis in central west brazil |
| topic | Paracoccidioidomycosis Treatment adherence and compliance loss to follow-up mycoses |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132019000200202&lng=en&tlng=en |
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