Collateral Circulation in Ischemic Stroke: An Updated Review
The collateral circulation plays a crucial role in maintaining perfusion to brain tissue in ischemic stroke, which prolongs the time window for effective therapies to be provided and ultimately avoids irreversible damage that may lead to worse clinical outcomes. The understanding of this complex vas...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Stroke Society
2023-05-01
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| Series: | Journal of Stroke |
| Subjects: | |
| Online Access: | http://www.j-stroke.org/upload/pdf/jos-2022-02936.pdf |
| _version_ | 1797653526919249920 |
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| author | Gino Maguida Ashfaq Shuaib |
| author_facet | Gino Maguida Ashfaq Shuaib |
| author_sort | Gino Maguida |
| collection | DOAJ |
| description | The collateral circulation plays a crucial role in maintaining perfusion to brain tissue in ischemic stroke, which prolongs the time window for effective therapies to be provided and ultimately avoids irreversible damage that may lead to worse clinical outcomes. The understanding of this complex vascular bypass system has advanced greatly in the past few years, yet effective treatments for its potentiation as a therapeutic target remain a challenge. The assessment of the collateral circulation is now part of the routine neuroimaging protocols for acute ischemic stroke, which provides a more complete pathophysiological picture in each patient that allows for a better selection for acute reperfusion therapies and a more accurate prognostication of outcomes, among other potential uses. In this review, we aim to provide a structured and updated approach to the collateral circulation while highlighting ongoing research areas with promising future clinical applications. |
| first_indexed | 2024-03-11T16:45:51Z |
| format | Article |
| id | doaj.art-fdf67cd413ad4fde9f106f60fa7bc50c |
| institution | Directory Open Access Journal |
| issn | 2287-6391 2287-6405 |
| language | English |
| last_indexed | 2024-03-11T16:45:51Z |
| publishDate | 2023-05-01 |
| publisher | Korean Stroke Society |
| record_format | Article |
| series | Journal of Stroke |
| spelling | doaj.art-fdf67cd413ad4fde9f106f60fa7bc50c2023-10-23T00:17:46ZengKorean Stroke SocietyJournal of Stroke2287-63912287-64052023-05-0125217919810.5853/jos.2022.02936475Collateral Circulation in Ischemic Stroke: An Updated ReviewGino Maguida0Ashfaq Shuaib1 Stroke Program, Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, Canada Stroke Program, Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, CanadaThe collateral circulation plays a crucial role in maintaining perfusion to brain tissue in ischemic stroke, which prolongs the time window for effective therapies to be provided and ultimately avoids irreversible damage that may lead to worse clinical outcomes. The understanding of this complex vascular bypass system has advanced greatly in the past few years, yet effective treatments for its potentiation as a therapeutic target remain a challenge. The assessment of the collateral circulation is now part of the routine neuroimaging protocols for acute ischemic stroke, which provides a more complete pathophysiological picture in each patient that allows for a better selection for acute reperfusion therapies and a more accurate prognostication of outcomes, among other potential uses. In this review, we aim to provide a structured and updated approach to the collateral circulation while highlighting ongoing research areas with promising future clinical applications.http://www.j-stroke.org/upload/pdf/jos-2022-02936.pdfischemic strokecerebrovascular circulationcollateral circulationthrombolytic therapythrombectomy |
| spellingShingle | Gino Maguida Ashfaq Shuaib Collateral Circulation in Ischemic Stroke: An Updated Review Journal of Stroke ischemic stroke cerebrovascular circulation collateral circulation thrombolytic therapy thrombectomy |
| title | Collateral Circulation in Ischemic Stroke: An Updated Review |
| title_full | Collateral Circulation in Ischemic Stroke: An Updated Review |
| title_fullStr | Collateral Circulation in Ischemic Stroke: An Updated Review |
| title_full_unstemmed | Collateral Circulation in Ischemic Stroke: An Updated Review |
| title_short | Collateral Circulation in Ischemic Stroke: An Updated Review |
| title_sort | collateral circulation in ischemic stroke an updated review |
| topic | ischemic stroke cerebrovascular circulation collateral circulation thrombolytic therapy thrombectomy |
| url | http://www.j-stroke.org/upload/pdf/jos-2022-02936.pdf |
| work_keys_str_mv | AT ginomaguida collateralcirculationinischemicstrokeanupdatedreview AT ashfaqshuaib collateralcirculationinischemicstrokeanupdatedreview |