A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/11/2018 |
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| author | Yasunobu Yamashita Takanori Yoshikawa Hirofumi Yamazaki Yuki Kawaji Takashi Tamura Keiichi Hatamaru Masahiro Itonaga Reiko Ashida Yoshiyuki Ida Takao Maekita Mikitaka Iguchi Masayuki Kitano |
| author_facet | Yasunobu Yamashita Takanori Yoshikawa Hirofumi Yamazaki Yuki Kawaji Takashi Tamura Keiichi Hatamaru Masahiro Itonaga Reiko Ashida Yoshiyuki Ida Takao Maekita Mikitaka Iguchi Masayuki Kitano |
| author_sort | Yasunobu Yamashita |
| collection | DOAJ |
| description | Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between January 2019 and January 2020, 53 patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS were enrolled. The ability of DFI-EUS and e-FLOW EUS to detect vessels was compared with that of contrast-enhanced EUS. This article describes the DFI technique along with our first experience of its use for vascular assessment of pancreatobiliary lesions. Vessels were imaged in 34 pancreatic solid lesions, eight intraductal papillary mucinous neoplasms (IPMNs), seven gall bladder lesions, and four swollen lymph nodes. DFI-EUS (91%) was significantly superior to e-FLOW EUS (53%) with respect to detection of vessels (<i>p</i> < 0.001) and for discrimination of mural nodules from mucous clots in IPMN and gallbladder lesions from sludge (<i>p</i> = 0.046). Thus, DFI-EUS has the potential to become an essential tool for diagnosis and vascular assessment of various diseases. |
| first_indexed | 2024-03-10T05:34:59Z |
| format | Article |
| id | doaj.art-fdf7398115ee4e709cd42669ee1c68c4 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T05:34:59Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-fdf7398115ee4e709cd42669ee1c68c42023-11-22T23:01:09ZengMDPI AGDiagnostics2075-44182021-10-011111201810.3390/diagnostics11112018A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory StudyYasunobu Yamashita0Takanori Yoshikawa1Hirofumi Yamazaki2Yuki Kawaji3Takashi Tamura4Keiichi Hatamaru5Masahiro Itonaga6Reiko Ashida7Yoshiyuki Ida8Takao Maekita9Mikitaka Iguchi10Masayuki Kitano11Second Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanClinical Study Support Center, Wakayama Medical University Hospital, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanSecond Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, JapanDetective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between January 2019 and January 2020, 53 patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS were enrolled. The ability of DFI-EUS and e-FLOW EUS to detect vessels was compared with that of contrast-enhanced EUS. This article describes the DFI technique along with our first experience of its use for vascular assessment of pancreatobiliary lesions. Vessels were imaged in 34 pancreatic solid lesions, eight intraductal papillary mucinous neoplasms (IPMNs), seven gall bladder lesions, and four swollen lymph nodes. DFI-EUS (91%) was significantly superior to e-FLOW EUS (53%) with respect to detection of vessels (<i>p</i> < 0.001) and for discrimination of mural nodules from mucous clots in IPMN and gallbladder lesions from sludge (<i>p</i> = 0.046). Thus, DFI-EUS has the potential to become an essential tool for diagnosis and vascular assessment of various diseases.https://www.mdpi.com/2075-4418/11/11/2018detective flow imaging endoscopic ultrasonographydoppler endoscopic ultrasonographyvessel detectionnovel techniquecontrast-enhanced endoscopic ultrasonographypancreatobiliary lesion |
| spellingShingle | Yasunobu Yamashita Takanori Yoshikawa Hirofumi Yamazaki Yuki Kawaji Takashi Tamura Keiichi Hatamaru Masahiro Itonaga Reiko Ashida Yoshiyuki Ida Takao Maekita Mikitaka Iguchi Masayuki Kitano A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study Diagnostics detective flow imaging endoscopic ultrasonography doppler endoscopic ultrasonography vessel detection novel technique contrast-enhanced endoscopic ultrasonography pancreatobiliary lesion |
| title | A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study |
| title_full | A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study |
| title_fullStr | A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study |
| title_full_unstemmed | A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study |
| title_short | A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study |
| title_sort | novel endoscopic ultrasonography imaging technique for depicting microcirculation in pancreatobiliary lesions without the need for contrast enhancement a prospective exploratory study |
| topic | detective flow imaging endoscopic ultrasonography doppler endoscopic ultrasonography vessel detection novel technique contrast-enhanced endoscopic ultrasonography pancreatobiliary lesion |
| url | https://www.mdpi.com/2075-4418/11/11/2018 |
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