Inferring novel indications of approved drugs via a learning method with local and global consistency.

Inferring new indication of approved drugs is critical not only for the elucidation of the interaction mechanisms between these drugs and their associated diseases, but also for the development of drug therapy for various human diseases. This paper proposes a network-based approach to reveal the ass...

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Bibliographic Details
Main Authors: Yan Yan, Xinwei Shao, Zhenran Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182043?pdf=render

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