Inferring novel indications of approved drugs via a learning method with local and global consistency.
Inferring new indication of approved drugs is critical not only for the elucidation of the interaction mechanisms between these drugs and their associated diseases, but also for the development of drug therapy for various human diseases. This paper proposes a network-based approach to reveal the ass...
Main Authors: | Yan Yan, Xinwei Shao, Zhenran Jiang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4182043?pdf=render |
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