Pharmacological actions of dieckol on modulation of platelet functions and thrombus formation via integrin αIIbβ3 and cAMP signaling
Background and purpose: Dieckol is a phlorotannin that can be found in seaweeds, particularly in Eisenia bicyclis (brown algae) and is known to have anti-oxidant, anti-inflammatory, and anti-microbial properties. It also possesses anti-thrombotic and pro-fibrinolytic activities; however, the mechani...
Main Authors: | Muhammad Irfan, Tae-Hyung Kwon, Hyuk-Woo Kwon, Man Hee Rhee |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-03-01
|
Series: | Pharmacological Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1043661822000330 |
Similar Items
-
Structure, signal transduction, activation, and inhibition of integrin αIIbβ3
by: Honglei Xin, et al.
Published: (2023-02-01) -
Synergistic effect of peptide inhibitors derived from the extracellular and intracellular domain of αIIb subunit of integrin αIIbβ3 on platelet activation and aggregation
by: Alexia V. Gkourogianni, et al.
Published: (2018-01-01) -
Maximum likelihood approach suggests positive selection in platelet integrin αIIbβ3 in mammalian species
by: Luís Bernardo Pina-Cabral, et al.
Published: (2019-05-01) -
Exogenous Integrin αIIbβ3 Inhibitors Revisited: Past, Present and Future Applications
by: Danique L. van den Kerkhof, et al.
Published: (2021-03-01) -
Reconstitution of Functional Integrin αIIbβ3 and Its Activation in Plasma Membrane-Mimetic Lipid Environments
by: Una Janke, et al.
Published: (2021-06-01)