Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways

Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways

The development of vaccine adjuvants is of interest for the management of chronic diseases, cancer, and future pandemics. Therefore, the role of Toll-like receptors (TLRs) in the effects of vaccine adjuvants has been investigated. TLR4 ligand-based adjuvants are the most frequently used adjuvants fo...

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Bibliographic Details
Main Authors: Diego A. Díaz-Dinamarca, Michelle L. Salazar, Daniel F. Escobar, Byron N. Castillo, Bastián Valdebenito, Pablo Díaz, Augusto Manubens, Fabián Salazar, Mayarling F. Troncoso, Sergio Lavandero, Janepsy Díaz, María Inés Becker, Abel E. Vásquez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
protein-based adjuvants (PBAs)
TLR4 agonist
MyD88
TRIF
antigen-presenting cells
vaccines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1186188/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1186188/full

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