Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch th...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-07-01
|
| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1208190/full |
| _version_ | 1797782177970126848 |
|---|---|
| author | Elias Akiki Ali Ahmad Ali Ahmad Edward A. El-Am Ana I. Casanegra Kyle W. Klarich Reto Kurmann |
| author_facet | Elias Akiki Ali Ahmad Ali Ahmad Edward A. El-Am Ana I. Casanegra Kyle W. Klarich Reto Kurmann |
| author_sort | Elias Akiki |
| collection | DOAJ |
| description | An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy. |
| first_indexed | 2024-03-13T00:07:20Z |
| format | Article |
| id | doaj.art-fe083360170c407dbad943cd2bf9e2f3 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-03-13T00:07:20Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-fe083360170c407dbad943cd2bf9e2f32023-07-13T00:00:35ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-07-011010.3389/fcvm.2023.12081901208190Case report: New is not always better: treatment of non-bacterial thrombotic endocarditisElias Akiki0Ali Ahmad1Ali Ahmad2Edward A. El-Am3Ana I. Casanegra4Kyle W. Klarich5Reto Kurmann6Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDepartment of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesAn elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1208190/fullnon-bacterial thrombotic endocarditisanticoagulationembolic strokeheparinwarfarinDOAC |
| spellingShingle | Elias Akiki Ali Ahmad Ali Ahmad Edward A. El-Am Ana I. Casanegra Kyle W. Klarich Reto Kurmann Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis Frontiers in Cardiovascular Medicine non-bacterial thrombotic endocarditis anticoagulation embolic stroke heparin warfarin DOAC |
| title | Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis |
| title_full | Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis |
| title_fullStr | Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis |
| title_full_unstemmed | Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis |
| title_short | Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis |
| title_sort | case report new is not always better treatment of non bacterial thrombotic endocarditis |
| topic | non-bacterial thrombotic endocarditis anticoagulation embolic stroke heparin warfarin DOAC |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1208190/full |
| work_keys_str_mv | AT eliasakiki casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT aliahmad casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT aliahmad casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT edwardaelam casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT anaicasanegra casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT kylewklarich casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis AT retokurmann casereportnewisnotalwaysbettertreatmentofnonbacterialthromboticendocarditis |