Differential Effects of Overexpression of Wild Type and Kinase-Dead MELK in Fibroblasts and Keratinocytes, Potential Implications for Skin Wound Healing and Cancer

Differential Effects of Overexpression of Wild Type and Kinase-Dead MELK in Fibroblasts and Keratinocytes, Potential Implications for Skin Wound Healing and Cancer

Maternal embryonic leucine-zipper kinase (MELK) plays a significant role in cell cycle progression, mitosis, cell migration, cell renewal, gene expression, embryogenesis, proliferation, apoptosis, and spliceosome assembly. In addition, MELK is known to be overexpressed in multiple types of cancer an...

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Bibliographic Details
Main Authors:	Łukasz Szymański, Krystyna Lieto, Robert Zdanowski, Sławomir Lewicki, Jean-Pierre Tassan, Jacek Z. Kubiak
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	International Journal of Molecular Sciences
Subjects:	MELK ERK p38 MAPK JNK p53
Online Access:	https://www.mdpi.com/1422-0067/24/9/8089

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