Paclitaxel and other taxanes in hazelnut
Small amounts of paclitaxel (Taxol®) were isolated from Tombul hazelnut (Corylus arellana L.) hard shells, green shell covers and leaves. In addition to paclitaxel, 10-deacetyl baccatin III, baccatin III and cephalomannine were found in the extracts. Taxanes were not detected in nut kernels or hulls...
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| Format: | Article |
| Language: | English |
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Elsevier
2009-01-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464608000054 |
| _version_ | 1819293915306524672 |
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| author | Angela Hoffman Fereidoon Shahidi |
| author_facet | Angela Hoffman Fereidoon Shahidi |
| author_sort | Angela Hoffman |
| collection | DOAJ |
| description | Small amounts of paclitaxel (Taxol®) were isolated from Tombul hazelnut (Corylus arellana L.) hard shells, green shell covers and leaves. In addition to paclitaxel, 10-deacetyl baccatin III, baccatin III and cephalomannine were found in the extracts. Taxanes were not detected in nut kernels or hulls from this cultivar. The amounts present varied between 8.61 and 68.22 micrograms per gram sample on a defatted and dried basis. While it is possible that these taxanes may have been made by fungi associated with the hazelnut, it is likely that they are made by the plant tissues. |
| first_indexed | 2024-12-24T04:18:01Z |
| format | Article |
| id | doaj.art-fe0a4dc50c18482ca2491b5bc062d4b1 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-24T04:18:01Z |
| publishDate | 2009-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-fe0a4dc50c18482ca2491b5bc062d4b12022-12-21T17:15:53ZengElsevierJournal of Functional Foods1756-46462009-01-01113337Paclitaxel and other taxanes in hazelnutAngela Hoffman0Fereidoon Shahidi1Department of Chemistry, University of Portland, Portland, OR 97203, USA; Corresponding authors. Tel.: +1 503 943 7173; fax: +1 503 943 7784 (A.Hoffman), tel.: +1 709 737 8552; fax: +1 709 737 4000 (F.Shahidi).Department of Biochemistry, Memorial University of Newfoundland, St. John’s, NL, Canada A1B 3X9; Corresponding authors. Tel.: +1 503 943 7173; fax: +1 503 943 7784 (A.Hoffman), tel.: +1 709 737 8552; fax: +1 709 737 4000 (F.Shahidi).Small amounts of paclitaxel (Taxol®) were isolated from Tombul hazelnut (Corylus arellana L.) hard shells, green shell covers and leaves. In addition to paclitaxel, 10-deacetyl baccatin III, baccatin III and cephalomannine were found in the extracts. Taxanes were not detected in nut kernels or hulls from this cultivar. The amounts present varied between 8.61 and 68.22 micrograms per gram sample on a defatted and dried basis. While it is possible that these taxanes may have been made by fungi associated with the hazelnut, it is likely that they are made by the plant tissues.http://www.sciencedirect.com/science/article/pii/S1756464608000054TaxanesPaclitaxelHazelnutPacific yewcephalomannineBaccatinIIIAnti-cancer |
| spellingShingle | Angela Hoffman Fereidoon Shahidi Paclitaxel and other taxanes in hazelnut Journal of Functional Foods Taxanes Paclitaxel Hazelnut Pacific yewcephalomannine BaccatinIII Anti-cancer |
| title | Paclitaxel and other taxanes in hazelnut |
| title_full | Paclitaxel and other taxanes in hazelnut |
| title_fullStr | Paclitaxel and other taxanes in hazelnut |
| title_full_unstemmed | Paclitaxel and other taxanes in hazelnut |
| title_short | Paclitaxel and other taxanes in hazelnut |
| title_sort | paclitaxel and other taxanes in hazelnut |
| topic | Taxanes Paclitaxel Hazelnut Pacific yewcephalomannine BaccatinIII Anti-cancer |
| url | http://www.sciencedirect.com/science/article/pii/S1756464608000054 |
| work_keys_str_mv | AT angelahoffman paclitaxelandothertaxanesinhazelnut AT fereidoonshahidi paclitaxelandothertaxanesinhazelnut |