Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study

Introduction Follicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of IVF outcomes. Material and methods This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility...

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Main Authors: Ana Jeremic, Zeljko Mikovic, Emina Sudar-Milovanovic, Esma R Isenovic, Milan Perovic
Format: Article
Language:English
Published: Termedia Publishing House 2021-08-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/Follicular-and-serum-levels-of-vitamin-D-in-women-with-unexplained-infertility-and,141185,0,2.html
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author Ana Jeremic
Zeljko Mikovic
Emina Sudar-Milovanovic
Esma R Isenovic
Milan Perovic
author_facet Ana Jeremic
Zeljko Mikovic
Emina Sudar-Milovanovic
Esma R Isenovic
Milan Perovic
author_sort Ana Jeremic
collection DOAJ
description Introduction Follicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of IVF outcomes. Material and methods This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring Vitamin D. Results Results show only a positive correlation between follicular and serum levels of Vitamin D (Rho=0.615, p=0.025) and between follicular levels of Vitamin D with the percentage of embryo fragmentation (Rho=0.544; p=0.036). Conclusions Results suggests that serum and follicular fluid vitamin D measurements could be complementary tools to the routine assessment of embryos.
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spelling doaj.art-fe0bf1e1678e4bfba2890475f5fa9ab02022-12-22T04:32:23ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512021-08-011751418142210.5114/aoms/141185141185Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot studyAna Jeremic0Zeljko Mikovic1Emina Sudar-Milovanovic2Esma R Isenovic3Milan Perovic4Clinic for Gynaecology and Obstetrics, “Narodni front”, Belgrade, SerbiaClinic for Gynaecology and Obstetrics, “Narodni front”, Belgrade, SerbiaInstitute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Belgrade, SerbiaDepartment of Radiobiology and Molecular Genetics, VINČA Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, Belgrade, SerbiaClinic for Gynaecology and Obstetrics, “Narodni front”, Belgrade, SerbiaIntroduction Follicular and serum vitamin D are considered potential markers of the oocyte and embryos' quality and predictors of IVF outcomes. Material and methods This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring Vitamin D. Results Results show only a positive correlation between follicular and serum levels of Vitamin D (Rho=0.615, p=0.025) and between follicular levels of Vitamin D with the percentage of embryo fragmentation (Rho=0.544; p=0.036). Conclusions Results suggests that serum and follicular fluid vitamin D measurements could be complementary tools to the routine assessment of embryos.https://www.archivesofmedicalscience.com/Follicular-and-serum-levels-of-vitamin-D-in-women-with-unexplained-infertility-and,141185,0,2.htmlvitamin dfollicular fluidart outcome
spellingShingle Ana Jeremic
Zeljko Mikovic
Emina Sudar-Milovanovic
Esma R Isenovic
Milan Perovic
Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
Archives of Medical Science
vitamin d
follicular fluid
art outcome
title Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
title_full Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
title_fullStr Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
title_full_unstemmed Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
title_short Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study
title_sort follicular and serum levels of vitamin d in women with unexplained infertility and their relationship with in vitro fertilization outcome an observational pilot study
topic vitamin d
follicular fluid
art outcome
url https://www.archivesofmedicalscience.com/Follicular-and-serum-levels-of-vitamin-D-in-women-with-unexplained-infertility-and,141185,0,2.html
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