Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma
Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma. Accumulating studies have reveal...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-09-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2020.01633/full |
| _version_ | 1819143701112291328 |
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| author | Wei Wu Yunxiang Zhou Yali Wang Lihong Liu Jianyao Lou Yongchuan Deng Peng Zhao Anwen Shao |
| author_facet | Wei Wu Yunxiang Zhou Yali Wang Lihong Liu Jianyao Lou Yongchuan Deng Peng Zhao Anwen Shao |
| author_sort | Wei Wu |
| collection | DOAJ |
| description | Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma. Accumulating studies have revealed the crucial clinical significance of SSTR2 in meningioma. Summarizing the progress of these studies is urgently needed as it may not only provide novel and better management for patients with meningioma but also indicate the direction of future research. Pertinent literature is reviewed to summarize the recent collective knowledge and understanding of SSTR2’s clinical significance in meningioma in this review. SSTR2 offers novel ideas and approaches in the diagnosis, treatment, and prognostic prediction for meningioma, but more and further studies are required. |
| first_indexed | 2024-12-22T12:30:25Z |
| format | Article |
| id | doaj.art-fe0c036409794eba8546ea2dd3700bd7 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-22T12:30:25Z |
| publishDate | 2020-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-fe0c036409794eba8546ea2dd3700bd72022-12-21T18:25:41ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2020-09-011010.3389/fonc.2020.01633560477Clinical Significance of Somatostatin Receptor (SSTR) 2 in MeningiomaWei Wu0Yunxiang Zhou1Yali Wang2Lihong Liu3Jianyao Lou4Yongchuan Deng5Peng Zhao6Anwen Shao7Department of Medical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Radiation Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Surgical Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Medical Oncology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaSomatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma. Accumulating studies have revealed the crucial clinical significance of SSTR2 in meningioma. Summarizing the progress of these studies is urgently needed as it may not only provide novel and better management for patients with meningioma but also indicate the direction of future research. Pertinent literature is reviewed to summarize the recent collective knowledge and understanding of SSTR2’s clinical significance in meningioma in this review. SSTR2 offers novel ideas and approaches in the diagnosis, treatment, and prognostic prediction for meningioma, but more and further studies are required.https://www.frontiersin.org/article/10.3389/fonc.2020.01633/fullmeningiomaSSTR2somatostatinsomatostatin analogsdiagnosistreatment |
| spellingShingle | Wei Wu Yunxiang Zhou Yali Wang Lihong Liu Jianyao Lou Yongchuan Deng Peng Zhao Anwen Shao Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma Frontiers in Oncology meningioma SSTR2 somatostatin somatostatin analogs diagnosis treatment |
| title | Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma |
| title_full | Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma |
| title_fullStr | Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma |
| title_full_unstemmed | Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma |
| title_short | Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma |
| title_sort | clinical significance of somatostatin receptor sstr 2 in meningioma |
| topic | meningioma SSTR2 somatostatin somatostatin analogs diagnosis treatment |
| url | https://www.frontiersin.org/article/10.3389/fonc.2020.01633/full |
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