Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum

OBJECTIVE: To investigate the relationship between Helicobacter pylori (H. py lori) infection and hyperemesis gravidarum (HG) by using H. pylori specific serum antibody test and H. pylori stool antigen (HpSA). MATERIAL AND METHODS: This prospective cross-sectional study was carried out on 70 pregnan...

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Main Authors: Emel Ebru Özçimen, Ayla Üçkuyu, Işık Üstüner, Filiz Fatma Yanık, Sevsen Kulaksızoğlu, Mesut Öktem, Derya Eroğlu, Esra Kuşçu
Format: Article
Language:English
Published: Medical Network 2006-12-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:http://gorm.com.tr/index.php/GORM/article/view/595
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author Emel Ebru Özçimen
Ayla Üçkuyu
Işık Üstüner
Filiz Fatma Yanık
Sevsen Kulaksızoğlu
Mesut Öktem
Derya Eroğlu
Esra Kuşçu
author_facet Emel Ebru Özçimen
Ayla Üçkuyu
Işık Üstüner
Filiz Fatma Yanık
Sevsen Kulaksızoğlu
Mesut Öktem
Derya Eroğlu
Esra Kuşçu
author_sort Emel Ebru Özçimen
collection DOAJ
description OBJECTIVE: To investigate the relationship between Helicobacter pylori (H. py lori) infection and hyperemesis gravidarum (HG) by using H. pylori specific serum antibody test and H. pylori stool antigen (HpSA). MATERIAL AND METHODS: This prospective cross-sectional study was carried out on 70 pregnant women with HG and 70 healthy pregnant women. Serum immunoglobulin G antibody for H. pylori and HpSA were assayed in both groups. Chi-square test was used f or statistical analysis. RESULTS: The study and control groups were matched regarding the maternal age, gestational weeks, gravida and parity. Positive serum IgG concentrations were found in 35 of the 70 HG patients (50%) compared with 33 of 70 controls (47.1%), (p>0.05). The rate of HpSA positivity was 32.8% (23/70) and 21.4% (15/70) respectiv ely (p>0.05). CONCLUSION: Contradicting with most of the studies which investigated the relationship between H. pylori infection and HG, our results indicate no significant relationship between HG and H. pylori IgG and HpSA.
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spelling doaj.art-fe0c04113210414e9d4d17665243e05c2023-02-15T16:10:15ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512006-12-01123529Helicobacter Pylori Positivity in Patients with Hyperemesis GravidarumEmel Ebru Özçimen0Ayla Üçkuyu1Işık Üstüner2Filiz Fatma Yanık3Sevsen Kulaksızoğlu4Mesut Öktem5Derya Eroğlu6Esra Kuşçu7Department of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaBaşkent University Department of Biochemistry, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaDepartment of Obstetrics and Gynecology, Başkent University, Konya Medical and Research Center, KonyaOBJECTIVE: To investigate the relationship between Helicobacter pylori (H. py lori) infection and hyperemesis gravidarum (HG) by using H. pylori specific serum antibody test and H. pylori stool antigen (HpSA). MATERIAL AND METHODS: This prospective cross-sectional study was carried out on 70 pregnant women with HG and 70 healthy pregnant women. Serum immunoglobulin G antibody for H. pylori and HpSA were assayed in both groups. Chi-square test was used f or statistical analysis. RESULTS: The study and control groups were matched regarding the maternal age, gestational weeks, gravida and parity. Positive serum IgG concentrations were found in 35 of the 70 HG patients (50%) compared with 33 of 70 controls (47.1%), (p>0.05). The rate of HpSA positivity was 32.8% (23/70) and 21.4% (15/70) respectiv ely (p>0.05). CONCLUSION: Contradicting with most of the studies which investigated the relationship between H. pylori infection and HG, our results indicate no significant relationship between HG and H. pylori IgG and HpSA.http://gorm.com.tr/index.php/GORM/article/view/595Helicobacter pylori, Hyperemesis gravidarum, Helicobacter pylori stool antigen, Helicobacter pylori seropositivity
spellingShingle Emel Ebru Özçimen
Ayla Üçkuyu
Işık Üstüner
Filiz Fatma Yanık
Sevsen Kulaksızoğlu
Mesut Öktem
Derya Eroğlu
Esra Kuşçu
Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
Gynecology Obstetrics & Reproductive Medicine
Helicobacter pylori, Hyperemesis gravidarum, Helicobacter pylori stool antigen, Helicobacter pylori seropositivity
title Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
title_full Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
title_fullStr Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
title_full_unstemmed Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
title_short Helicobacter Pylori Positivity in Patients with Hyperemesis Gravidarum
title_sort helicobacter pylori positivity in patients with hyperemesis gravidarum
topic Helicobacter pylori, Hyperemesis gravidarum, Helicobacter pylori stool antigen, Helicobacter pylori seropositivity
url http://gorm.com.tr/index.php/GORM/article/view/595
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