A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh
To date, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 80 million people globally. We report a case series of five clinically and laboratory confirmed COVID-19 patients from Bangladesh who suffered a second episode of COVID-19 illness after 70 symptom-free days. The...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/6/2/41 |
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| author | Pritimoy Das Syed M. Satter Allen G. Ross Zarin Abdullah Arifa Nazneen Rebeca Sultana Nadia Ali Rimi Kamal Chowdhury Rashedul Alam Shahana Parveen Md Mahfuzur Rahman Mohammad Enayet Hossain Mohammed Ziaur Rahman Razib Mazumder Ahmed Abdullah Mahmudur Rahman Sayera Banu Tahmeed Ahmed John D. Clemens Mustafizur Rahman |
| author_facet | Pritimoy Das Syed M. Satter Allen G. Ross Zarin Abdullah Arifa Nazneen Rebeca Sultana Nadia Ali Rimi Kamal Chowdhury Rashedul Alam Shahana Parveen Md Mahfuzur Rahman Mohammad Enayet Hossain Mohammed Ziaur Rahman Razib Mazumder Ahmed Abdullah Mahmudur Rahman Sayera Banu Tahmeed Ahmed John D. Clemens Mustafizur Rahman |
| author_sort | Pritimoy Das |
| collection | DOAJ |
| description | To date, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 80 million people globally. We report a case series of five clinically and laboratory confirmed COVID-19 patients from Bangladesh who suffered a second episode of COVID-19 illness after 70 symptom-free days. The International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), is a leading public health research institution in South Asia. icddr, b staff were actively tested, treated and followed-up for COVID-19 by an experienced team of clinicians, epidemiologists, and virologists. From 21 March to 30 September 2020, 1370 icddr,b employees working at either the Dhaka (urban) or Matlab (rural) clinical sites were tested for COVID-19. In total, 522 (38%) were positive; 38% from urban Dhaka (483/1261) and 36% from the rural clinical site Matlab (39/109). Five patients (60% male with a mean age of 41 years) had real-time reverse transcription-polymerase chain reaction (rRT-PCR) diagnosed recurrence (reinfection) of SARS-CoV-2. All had mild symptoms except for one who was hospitalized. Though all cases reported fair risk perceptions towards COVID-19, all had potential exposure sources for reinfection. After a second course of treatment and home isolation, all patients fully recovered. Our findings suggest the need for COVID-19 vaccination and continuing other preventive measures to further mitigate the pandemic. An optimal post-recovery follow-up strategy to allow the safe return of COVID-19 patients to the workforce may be considered. |
| first_indexed | 2024-03-10T12:45:04Z |
| format | Article |
| id | doaj.art-fe0fb208b9764b9bab8536170b59061f |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-10T12:45:04Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-fe0fb208b9764b9bab8536170b59061f2023-11-21T13:33:45ZengMDPI AGTropical Medicine and Infectious Disease2414-63662021-03-01624110.3390/tropicalmed6020041A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in BangladeshPritimoy Das0Syed M. Satter1Allen G. Ross2Zarin Abdullah3Arifa Nazneen4Rebeca Sultana5Nadia Ali Rimi6Kamal Chowdhury7Rashedul Alam8Shahana Parveen9Md Mahfuzur Rahman10Mohammad Enayet Hossain11Mohammed Ziaur Rahman12Razib Mazumder13Ahmed Abdullah14Mahmudur Rahman15Sayera Banu16Tahmeed Ahmed17John D. Clemens18Mustafizur Rahman19International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, BangladeshTo date, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 80 million people globally. We report a case series of five clinically and laboratory confirmed COVID-19 patients from Bangladesh who suffered a second episode of COVID-19 illness after 70 symptom-free days. The International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), is a leading public health research institution in South Asia. icddr, b staff were actively tested, treated and followed-up for COVID-19 by an experienced team of clinicians, epidemiologists, and virologists. From 21 March to 30 September 2020, 1370 icddr,b employees working at either the Dhaka (urban) or Matlab (rural) clinical sites were tested for COVID-19. In total, 522 (38%) were positive; 38% from urban Dhaka (483/1261) and 36% from the rural clinical site Matlab (39/109). Five patients (60% male with a mean age of 41 years) had real-time reverse transcription-polymerase chain reaction (rRT-PCR) diagnosed recurrence (reinfection) of SARS-CoV-2. All had mild symptoms except for one who was hospitalized. Though all cases reported fair risk perceptions towards COVID-19, all had potential exposure sources for reinfection. After a second course of treatment and home isolation, all patients fully recovered. Our findings suggest the need for COVID-19 vaccination and continuing other preventive measures to further mitigate the pandemic. An optimal post-recovery follow-up strategy to allow the safe return of COVID-19 patients to the workforce may be considered.https://www.mdpi.com/2414-6366/6/2/41COVID-19recurrencereinfectionBangladesh |
| spellingShingle | Pritimoy Das Syed M. Satter Allen G. Ross Zarin Abdullah Arifa Nazneen Rebeca Sultana Nadia Ali Rimi Kamal Chowdhury Rashedul Alam Shahana Parveen Md Mahfuzur Rahman Mohammad Enayet Hossain Mohammed Ziaur Rahman Razib Mazumder Ahmed Abdullah Mahmudur Rahman Sayera Banu Tahmeed Ahmed John D. Clemens Mustafizur Rahman A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh Tropical Medicine and Infectious Disease COVID-19 recurrence reinfection Bangladesh |
| title | A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh |
| title_full | A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh |
| title_fullStr | A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh |
| title_full_unstemmed | A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh |
| title_short | A Case Series Describing the Recurrence of COVID-19 in Patients Who Recovered from Initial Illness in Bangladesh |
| title_sort | case series describing the recurrence of covid 19 in patients who recovered from initial illness in bangladesh |
| topic | COVID-19 recurrence reinfection Bangladesh |
| url | https://www.mdpi.com/2414-6366/6/2/41 |
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