Astaxanthin Inhibits H<sub>2</sub>O<sub>2</sub>-Induced Excessive Mitophagy and Apoptosis in SH-SY5Y Cells by Regulation of Akt/mTOR Activation

Astaxanthin Inhibits H<sub>2</sub>O<sub>2</sub>-Induced Excessive Mitophagy and Apoptosis in SH-SY5Y Cells by Regulation of Akt/mTOR Activation

Oxidative stress, which damages cellular components and causes mitochondrial dysfunction, occurs in a variety of human diseases, including neurological disorders. The clearance of damaged mitochondria via mitophagy maintains the normal function of mitochondria and facilitates cell survival. Astaxant...

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Bibliographic Details
Main Authors: Tingting Yan, Feng Ding, Yiting Zhang, Yalin Wang, Yinuo Wang, Yuanqingzhi Zhang, Feiyu Zhu, Guanghan Zhang, Xinyi Zheng, Guangyin Jia, Feng Zhou, Yu Zhao, Yan Zhao
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
astaxanthin
H<sub>2</sub>O<sub>2</sub>
Akt/mTOR
apoptosis
mitophagy
Online Access:https://www.mdpi.com/1660-3397/22/2/57

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