Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity
Amiodarone is an effective anti-arrhythmic agent widely used for management of supraventricular and ventricular arrhythmias. Amiodarone-induced pulmonary toxicity is one of the most serious side effects of amiodarone therapy. Patients who have developed pulmonary toxicity usually present with nonspe...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2022-01-01
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| Series: | Van Tıp Dergisi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-07348 |
| _version_ | 1827608564218200064 |
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| author | Nuri Köse Tarık Yıldırım |
| author_facet | Nuri Köse Tarık Yıldırım |
| author_sort | Nuri Köse |
| collection | DOAJ |
| description | Amiodarone is an effective anti-arrhythmic agent widely used for management of supraventricular and ventricular arrhythmias. Amiodarone-induced pulmonary toxicity is one of the most serious side effects of amiodarone therapy. Patients who have developed pulmonary toxicity usually present with nonspecific symptoms such as cough, dyspnea, fever, and weight loss. Radiologically, amiodarone toxicity can manifest as a focal lesion or diffuse interstitial abnormality. Treatment involves immediate discontinuation of amiodarone and administration of corticosteroids for prompt recovery. Because of its long elimination half-life, pulmonary toxicity may initially progress despite drug discontinuation and may recur upon steroid withdrawal. In this manuscript, we presented a 62 years-old woman who developed pulmonary toxicity due to amiodarone therapy, recovered with corticosteroid therapy but relapsed after stopping this therapy, and finally recovered completely after long term use of steroid therapy. |
| first_indexed | 2024-03-09T07:16:08Z |
| format | Article |
| id | doaj.art-fe11ab5bd0c044b9a51739dd17299df0 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T07:16:08Z |
| publishDate | 2022-01-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-fe11ab5bd0c044b9a51739dd17299df02023-12-03T08:39:32ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512022-01-0129113614010.5505/vtd.2022.07348VTD-07348Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary ToxicityNuri Köse0Tarık Yıldırım1Department Of Cardiology, Yücelen Hospital, Muğla, TurkeyDepartment Of Cardiology, Balıkesir University Faculty Of Medicine, Balıkesir, TurkeyAmiodarone is an effective anti-arrhythmic agent widely used for management of supraventricular and ventricular arrhythmias. Amiodarone-induced pulmonary toxicity is one of the most serious side effects of amiodarone therapy. Patients who have developed pulmonary toxicity usually present with nonspecific symptoms such as cough, dyspnea, fever, and weight loss. Radiologically, amiodarone toxicity can manifest as a focal lesion or diffuse interstitial abnormality. Treatment involves immediate discontinuation of amiodarone and administration of corticosteroids for prompt recovery. Because of its long elimination half-life, pulmonary toxicity may initially progress despite drug discontinuation and may recur upon steroid withdrawal. In this manuscript, we presented a 62 years-old woman who developed pulmonary toxicity due to amiodarone therapy, recovered with corticosteroid therapy but relapsed after stopping this therapy, and finally recovered completely after long term use of steroid therapy.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-07348amiodaronetoxicitycardiomyopathyhypertrophicatrial fibrillation |
| spellingShingle | Nuri Köse Tarık Yıldırım Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity Van Tıp Dergisi amiodarone toxicity cardiomyopathy hypertrophic atrial fibrillation |
| title | Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity |
| title_full | Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity |
| title_fullStr | Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity |
| title_full_unstemmed | Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity |
| title_short | Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity |
| title_sort | amiodarone induced pulmonary toxicity in a patient with paroxysmal atrial fibrillation and recurrence of pulmonary toxicity |
| topic | amiodarone toxicity cardiomyopathy hypertrophic atrial fibrillation |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-07348 |
| work_keys_str_mv | AT nurikose amiodaroneinducedpulmonarytoxicityinapatientwithparoxysmalatrialfibrillationandrecurrenceofpulmonarytoxicity AT tarıkyıldırım amiodaroneinducedpulmonarytoxicityinapatientwithparoxysmalatrialfibrillationandrecurrenceofpulmonarytoxicity |