Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging
Skin is the largest and most complex organ in the human body comprised of multiple layers with different types of cells. Different kinds of environmental stressors, for example, ultraviolet radiation (UVR), temperature, air pollutants, smoking, and diet, accelerate skin aging by stimulating inflamma...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/8/3974 |
| _version_ | 1797537964240142336 |
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| author | Tuba M. Ansary Md. Razib Hossain Koji Kamiya Mayumi Komine Mamitaro Ohtsuki |
| author_facet | Tuba M. Ansary Md. Razib Hossain Koji Kamiya Mayumi Komine Mamitaro Ohtsuki |
| author_sort | Tuba M. Ansary |
| collection | DOAJ |
| description | Skin is the largest and most complex organ in the human body comprised of multiple layers with different types of cells. Different kinds of environmental stressors, for example, ultraviolet radiation (UVR), temperature, air pollutants, smoking, and diet, accelerate skin aging by stimulating inflammatory molecules. Skin aging caused by UVR is characterized by loss of elasticity, fine lines, wrinkles, reduced epidermal and dermal components, increased epidermal permeability, delayed wound healing, and approximately 90% of skin aging. These external factors can cause aging through reactive oxygen species (ROS)-mediated inflammation, as well as aged skin is a source of circulatory inflammatory molecules which accelerate skin aging and cause aging-related diseases. This review article focuses on the inflammatory pathways associated with UVR-mediated skin aging. |
| first_indexed | 2024-03-10T12:24:41Z |
| format | Article |
| id | doaj.art-fe11f14355824b40a69b363eb495c5b1 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T12:24:41Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-fe11f14355824b40a69b363eb495c5b12023-11-21T15:13:49ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-04-01228397410.3390/ijms22083974Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin AgingTuba M. Ansary0Md. Razib Hossain1Koji Kamiya2Mayumi Komine3Mamitaro Ohtsuki4Department of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, JapanDepartment of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, JapanDepartment of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, JapanDepartment of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, JapanDepartment of Dermatology, Faculty of Medicine, Jichi Medical University, Tochigi 329-0498, JapanSkin is the largest and most complex organ in the human body comprised of multiple layers with different types of cells. Different kinds of environmental stressors, for example, ultraviolet radiation (UVR), temperature, air pollutants, smoking, and diet, accelerate skin aging by stimulating inflammatory molecules. Skin aging caused by UVR is characterized by loss of elasticity, fine lines, wrinkles, reduced epidermal and dermal components, increased epidermal permeability, delayed wound healing, and approximately 90% of skin aging. These external factors can cause aging through reactive oxygen species (ROS)-mediated inflammation, as well as aged skin is a source of circulatory inflammatory molecules which accelerate skin aging and cause aging-related diseases. This review article focuses on the inflammatory pathways associated with UVR-mediated skin aging.https://www.mdpi.com/1422-0067/22/8/3974inflammationultraviolet radiation (UVR)skin aging |
| spellingShingle | Tuba M. Ansary Md. Razib Hossain Koji Kamiya Mayumi Komine Mamitaro Ohtsuki Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging International Journal of Molecular Sciences inflammation ultraviolet radiation (UVR) skin aging |
| title | Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging |
| title_full | Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging |
| title_fullStr | Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging |
| title_full_unstemmed | Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging |
| title_short | Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin Aging |
| title_sort | inflammatory molecules associated with ultraviolet radiation mediated skin aging |
| topic | inflammation ultraviolet radiation (UVR) skin aging |
| url | https://www.mdpi.com/1422-0067/22/8/3974 |
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