Identification of risk factors in pre-term infants with abnormal general movements
IntroductionThis study aimed to investigate the relationship between prenatal, perinatal, and postnatal risk factors for neurodevelopmental impairment (NDI) with the outcomes of General Movement (GM) Assessment (GMA) in pre-term infants at 3–5 months of age. We sought to identify the risk factors as...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.850877/full |
| _version_ | 1798015350029156352 |
|---|---|
| author | Małgorzata Domagalska-Szopa Andrzej Szopa Andrzej Szopa María Eugenia Serrano-Gómez María Eugenia Serrano-Gómez Magdalena Hagner-Derengowska Jakub Behrendt |
| author_facet | Małgorzata Domagalska-Szopa Andrzej Szopa Andrzej Szopa María Eugenia Serrano-Gómez María Eugenia Serrano-Gómez Magdalena Hagner-Derengowska Jakub Behrendt |
| author_sort | Małgorzata Domagalska-Szopa |
| collection | DOAJ |
| description | IntroductionThis study aimed to investigate the relationship between prenatal, perinatal, and postnatal risk factors for neurodevelopmental impairment (NDI) with the outcomes of General Movement (GM) Assessment (GMA) in pre-term infants at 3–5 months of age. We sought to identify the risk factors associated with the predictors of psychomotor development in pre-term newborns, such as normal fidgety movements (FMs), absent FMs, or abnormal FMs, assessed during the fidgety period of motor development.MethodsThe SYNAGIS program (prophylactic of Respiratory Syncytial Virus Infection) was used to identify risk factors for the development of neuromotor deficits in 164 pre-term infants who were at high risk of developing these deficits. Based on the GMA, all participants were divided into three groups of infants who presented: (1) normal FMs; (2) absent FMs; and (3) abnormal FMs.ResultsThe results of the current study suggest that abnormal GMs not only indicate commonly known factors like birth asphyxia (BA), respiratory distress syndrome (RDS), periventricular leukomalacia (PVL), intraventricular hemorrhage (IVH) grades 3–4, but also predict the development of motor impairments. In the present study, several specific risk factors including bronchopulmonary dysplasia (BPD), infertility treatments, maternal acute viral/bacterial infections during pregnancy, and elevated bilirubin levels were identified as attributes of an atypical fidgety movement pattern.ConclusionsAdditional clinical data, such as risk factors for NDI associated with early predictors of psychomotor development in pre-term newborns, i.e., absent or abnormal FMs, may be helpful in predicting neurological outcomes in pre-term infants with developmental concerns in the 1st month of life. |
| first_indexed | 2024-04-11T15:33:03Z |
| format | Article |
| id | doaj.art-fe139e7045fb4a97801478a5f38b6edd |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T15:33:03Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-fe139e7045fb4a97801478a5f38b6edd2022-12-22T04:16:06ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-11-011310.3389/fneur.2022.850877850877Identification of risk factors in pre-term infants with abnormal general movementsMałgorzata Domagalska-Szopa0Andrzej Szopa1Andrzej Szopa2María Eugenia Serrano-Gómez3María Eugenia Serrano-Gómez4Magdalena Hagner-Derengowska5Jakub Behrendt6Department of Developmental Age Physiotherapy, Medical University of Silesia, Katowice, PolandDepartment of Physiotherapy, Medical University of Silesia, Katowice, PolandRehabilitation and Medical Center Neuromed SC, Katowice, PolandFacultad de Enfermería y Rehabilitación, Universidad de La Sabana, Chía, ColombiaFacultad de Psicología Ciencias de la Educación y del Deporte Blanquerna, Universidad Ramon Llull, Barcelona, SpainFaculty of Earth Sciences and Spatial Management, University Nicolaus Copernicus, Toruń, PolandDepartment of Neonatal Intensive Care, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, PolandIntroductionThis study aimed to investigate the relationship between prenatal, perinatal, and postnatal risk factors for neurodevelopmental impairment (NDI) with the outcomes of General Movement (GM) Assessment (GMA) in pre-term infants at 3–5 months of age. We sought to identify the risk factors associated with the predictors of psychomotor development in pre-term newborns, such as normal fidgety movements (FMs), absent FMs, or abnormal FMs, assessed during the fidgety period of motor development.MethodsThe SYNAGIS program (prophylactic of Respiratory Syncytial Virus Infection) was used to identify risk factors for the development of neuromotor deficits in 164 pre-term infants who were at high risk of developing these deficits. Based on the GMA, all participants were divided into three groups of infants who presented: (1) normal FMs; (2) absent FMs; and (3) abnormal FMs.ResultsThe results of the current study suggest that abnormal GMs not only indicate commonly known factors like birth asphyxia (BA), respiratory distress syndrome (RDS), periventricular leukomalacia (PVL), intraventricular hemorrhage (IVH) grades 3–4, but also predict the development of motor impairments. In the present study, several specific risk factors including bronchopulmonary dysplasia (BPD), infertility treatments, maternal acute viral/bacterial infections during pregnancy, and elevated bilirubin levels were identified as attributes of an atypical fidgety movement pattern.ConclusionsAdditional clinical data, such as risk factors for NDI associated with early predictors of psychomotor development in pre-term newborns, i.e., absent or abnormal FMs, may be helpful in predicting neurological outcomes in pre-term infants with developmental concerns in the 1st month of life.https://www.frontiersin.org/articles/10.3389/fneur.2022.850877/fullpre-term infantsabnormal movementsrisk factorsgeneral movementsrisk factors identification |
| spellingShingle | Małgorzata Domagalska-Szopa Andrzej Szopa Andrzej Szopa María Eugenia Serrano-Gómez María Eugenia Serrano-Gómez Magdalena Hagner-Derengowska Jakub Behrendt Identification of risk factors in pre-term infants with abnormal general movements Frontiers in Neurology pre-term infants abnormal movements risk factors general movements risk factors identification |
| title | Identification of risk factors in pre-term infants with abnormal general movements |
| title_full | Identification of risk factors in pre-term infants with abnormal general movements |
| title_fullStr | Identification of risk factors in pre-term infants with abnormal general movements |
| title_full_unstemmed | Identification of risk factors in pre-term infants with abnormal general movements |
| title_short | Identification of risk factors in pre-term infants with abnormal general movements |
| title_sort | identification of risk factors in pre term infants with abnormal general movements |
| topic | pre-term infants abnormal movements risk factors general movements risk factors identification |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.850877/full |
| work_keys_str_mv | AT małgorzatadomagalskaszopa identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT andrzejszopa identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT andrzejszopa identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT mariaeugeniaserranogomez identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT mariaeugeniaserranogomez identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT magdalenahagnerderengowska identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements AT jakubbehrendt identificationofriskfactorsinpreterminfantswithabnormalgeneralmovements |