In vitro AND in silico EVALUATION OF THYMOQUINONE AS POTENTIAL ANTICANCER AGENT IN HUMAN ACUTE MYELOID LEUKEMIA HL-60 CELLS
This study aims to explore the cytotoxic, apoptotic and autophagic effects of thymoquinone on human acute myeloid leukemia. The cytotoxic effects of thymoquinone were determined with 3-(4, 5-dimethylthiazol-2-yl)-2 and 5-diphenyltetrazolium bromide (MTT) tests. B-cell lymphoma 2 associated X protein...
Main Author: | Neslihan Tekin Karacaer |
---|---|
Format: | Article |
Language: | English |
Published: |
Trakya University
2022-04-01
|
Series: | Trakya University Journal of Natural Sciences |
Subjects: | |
Online Access: | https://dergipark.org.tr/en/download/article-file/1989496 |
Similar Items
-
Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells
by: Futoon Abedrabbu Al-Rawashde, et al.
Published: (2022-09-01) -
The PI3K-Akt-mTOR Signaling Pathway in Human Acute Myeloid Leukemia (AML) Cells
by: Ina Nepstad, et al.
Published: (2020-04-01) -
Docetaxel Combined with Thymoquinone Induces Apoptosis in Prostate Cancer Cells via Inhibition of the PI3K/AKT Signaling Pathway
by: Santosh Kumar Singh, et al.
Published: (2019-09-01) -
Notopterol-induced apoptosis and differentiation in human acute myeloid leukemia HL-60 cells
by: Huang Q, et al.
Published: (2019-06-01) -
Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells
by: Belal Almajali, et al.
Published: (2022-03-01)