Defects in early synaptic formation and neuronal function in Prader-Willi syndrome

Abstract Prader-Willi syndrome (PWS), which is a complex epigenetic disorder caused by the deficiency of paternally expressed genes in chromosome 15q11-q13, is associated with several psychiatric dimensions, including autism spectrum disorder. We have previously reported that iPS cells derived from...

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Bibliographic Details
Main Authors: Shuhei Soeda, Daiki Ito, Tomoe Ogushi, Yui Sano, Ryosuke Negoro, Takuya Fujita, Ryo Saito, Hideo Taniura
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39065-x