Histone acetylation: a key determinant of acquired cisplatin resistance in cancer

Abstract Cisplatin is an alkylating class of chemotherapeutic drugs used to treat cancer patients. However, cisplatin fails in long-term treatment, and drug resistance is the primary reason for tumor recurrence. Hence, understanding the mechanism of acquirement of chemoresistance is essential for de...

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Bibliographic Details
Main Authors: Abhiram Natu, Tripti Verma, Bharat Khade, Rahul Thorat, Poonam Gera, Sangita Dhara, Sanjay Gupta
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Clinical Epigenetics
Subjects:
Online Access:https://doi.org/10.1186/s13148-023-01615-5