Regorafenib: from clinical research to clinical practice

Regorafenib is a new multiple tyrosine kinase inhibitor with anti-cancer and anti-angiogenic activity which application has been recently approved by the Russian Federation in patients with colon cancer and gastrointestinal tumors. The approval of application of regorafenib for the treatment of pati...

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Main Authors: M Yu Fedyanin, A A Tryakin
Format: Article
Language:Russian
Published: IP Habib O.N. 2017-09-01
Series:Современная онкология
Subjects:
Online Access:https://modernonco.orscience.ru/1815-1434/article/viewFile/27137/pdf
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author M Yu Fedyanin
A A Tryakin
author_facet M Yu Fedyanin
A A Tryakin
author_sort M Yu Fedyanin
collection DOAJ
description Regorafenib is a new multiple tyrosine kinase inhibitor with anti-cancer and anti-angiogenic activity which application has been recently approved by the Russian Federation in patients with colon cancer and gastrointestinal tumors. The approval of application of regorafenib for the treatment of patients with hepatocellular carcinoma is expected. This review discusses the main clinical studies of the drug: the steps of appointment, the prevention and the treatment of the complications using new tyrosine kinase inhibitor; the views of the Russian and foreign experts who should help chemotherapist in the clinical practice.
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spelling doaj.art-fe20a82fbfa74b63a6bfe38266be98ae2022-12-21T18:41:38ZrusIP Habib O.N.Современная онкология1815-14341815-14422017-09-01193192424357Regorafenib: from clinical research to clinical practiceM Yu Fedyanin0A A Tryakin1N.N.Blokhin National Medical Reseach Center of Oncology of the Ministry of Health of the Russian Federation.N.N.Blokhin National Medical Reseach Center of Oncology of the Ministry of Health of the Russian Federation.Regorafenib is a new multiple tyrosine kinase inhibitor with anti-cancer and anti-angiogenic activity which application has been recently approved by the Russian Federation in patients with colon cancer and gastrointestinal tumors. The approval of application of regorafenib for the treatment of patients with hepatocellular carcinoma is expected. This review discusses the main clinical studies of the drug: the steps of appointment, the prevention and the treatment of the complications using new tyrosine kinase inhibitor; the views of the Russian and foreign experts who should help chemotherapist in the clinical practice.https://modernonco.orscience.ru/1815-1434/article/viewFile/27137/pdfregorafenibcolon cancergastrointestinal tumorhepatocellular carcinoma
spellingShingle M Yu Fedyanin
A A Tryakin
Regorafenib: from clinical research to clinical practice
Современная онкология
regorafenib
colon cancer
gastrointestinal tumor
hepatocellular carcinoma
title Regorafenib: from clinical research to clinical practice
title_full Regorafenib: from clinical research to clinical practice
title_fullStr Regorafenib: from clinical research to clinical practice
title_full_unstemmed Regorafenib: from clinical research to clinical practice
title_short Regorafenib: from clinical research to clinical practice
title_sort regorafenib from clinical research to clinical practice
topic regorafenib
colon cancer
gastrointestinal tumor
hepatocellular carcinoma
url https://modernonco.orscience.ru/1815-1434/article/viewFile/27137/pdf
work_keys_str_mv AT myufedyanin regorafenibfromclinicalresearchtoclinicalpractice
AT aatryakin regorafenibfromclinicalresearchtoclinicalpractice