Effects of Regulatory T Cell Depletion in BALB/c Mice Infected with Low Doses of <i>Borrelia burgdorferi</i>

Effects of Regulatory T Cell Depletion in BALB/c Mice Infected with Low Doses of <i>Borrelia burgdorferi</i>

We previously demonstrated that a depletion of regulatory T (Treg) cells in Lyme arthritis-resistant C57BL/6 mice leads to pathological changes in the tibiotarsal joints following infection with <i>Borrelia burgdorferi</i>. Here, we assessed the effects of Treg cells on the response to &...

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Bibliographic Details
Main Authors: Kaitlyn N. Santiago, Tanya Kozlik, Elizabeth S. Liedhegner, Rebecca A. Slick, Michael W. Lawlor, Dean T. Nardelli
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pathogens
Subjects:
Lyme disease
Lyme borreliosis
regulatory T cells
Treg cells
arthritis
Lyme arthritis
Online Access:https://www.mdpi.com/2076-0817/12/2/189

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