Septal GABA and Glutamate Neurons Express RXFP3 mRNA and Depletion of Septal RXFP3 Impaired Spatial Search Strategy and Long-Term Reference Memory in Adult Mice

Septal GABA and Glutamate Neurons Express RXFP3 mRNA and Depletion of Septal RXFP3 Impaired Spatial Search Strategy and Long-Term Reference Memory in Adult Mice

Relaxin-3 is a highly conserved neuropeptide abundantly expressed in neurons of the nucleus incertus (NI), which project to nodes of the septohippocampal system (SHS) including the medial septum/diagonal band of Broca (MS/DB) and dorsal hippocampus, as well as to limbic circuits. High densities of t...

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Bibliographic Details
Main Authors: Mouna Haidar, Kimberly Tin, Cary Zhang, Mohsen Nategh, João Covita, Alexander D. Wykes, Jake Rogers, Andrew L. Gundlach
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroanatomy
Subjects:
relaxin-3
RXFP3
medial septum and diagonal band of Broca
spatial and reference memory
GABA neurons
glutamate neurons
Online Access:https://www.frontiersin.org/article/10.3389/fnana.2019.00030/full

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