Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison
Abstract We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-03-01
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| Series: | Clinical Hypertension |
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| Online Access: | http://link.springer.com/article/10.1186/s40885-018-0089-1 |
| _version_ | 1818370121920413696 |
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| author | Ravi Tejraj Mehta Anil Pareek Indranil Purkait |
| author_facet | Ravi Tejraj Mehta Anil Pareek Indranil Purkait |
| author_sort | Ravi Tejraj Mehta |
| collection | DOAJ |
| description | Abstract We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active controlled, phase 4, randomized trial” by Oh GC, et al. with interest. The authors aim to compare the efficacy of amlodipine or hydrochlorothiazide (HCTZ) with an ARB. However, we wish to highlight that chlorthalidone (CTD) is the evidence-based and recommended anti-hypertensive diuretic, and should replace HCTZ in the trial to effectively compare efficacy against the CCB amlodipine. |
| first_indexed | 2024-12-13T23:34:42Z |
| format | Article |
| id | doaj.art-fe21ec2239514ce988c34e25c82c0f8a |
| institution | Directory Open Access Journal |
| issn | 2056-5909 |
| language | English |
| last_indexed | 2024-12-13T23:34:42Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Clinical Hypertension |
| spelling | doaj.art-fe21ec2239514ce988c34e25c82c0f8a2022-12-21T23:27:20ZengBMCClinical Hypertension2056-59092018-03-012411210.1186/s40885-018-0089-1Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparisonRavi Tejraj Mehta0Anil Pareek1Indranil Purkait2Ipca Laboratories LimitedIpca Laboratories LimitedIpca Laboratories LimitedAbstract We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active controlled, phase 4, randomized trial” by Oh GC, et al. with interest. The authors aim to compare the efficacy of amlodipine or hydrochlorothiazide (HCTZ) with an ARB. However, we wish to highlight that chlorthalidone (CTD) is the evidence-based and recommended anti-hypertensive diuretic, and should replace HCTZ in the trial to effectively compare efficacy against the CCB amlodipine.http://link.springer.com/article/10.1186/s40885-018-0089-1ChlorthalidoneHydrochlorothiazideAmlodipineHypertensionThiazide diureticsCalcium channel blockers |
| spellingShingle | Ravi Tejraj Mehta Anil Pareek Indranil Purkait Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison Clinical Hypertension Chlorthalidone Hydrochlorothiazide Amlodipine Hypertension Thiazide diuretics Calcium channel blockers |
| title | Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison |
| title_full | Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison |
| title_fullStr | Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison |
| title_full_unstemmed | Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison |
| title_short | Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison |
| title_sort | chlorthalidone not hydrochlorothiazide is the right diuretic for comparison |
| topic | Chlorthalidone Hydrochlorothiazide Amlodipine Hypertension Thiazide diuretics Calcium channel blockers |
| url | http://link.springer.com/article/10.1186/s40885-018-0089-1 |
| work_keys_str_mv | AT ravitejrajmehta chlorthalidonenothydrochlorothiazideistherightdiureticforcomparison AT anilpareek chlorthalidonenothydrochlorothiazideistherightdiureticforcomparison AT indranilpurkait chlorthalidonenothydrochlorothiazideistherightdiureticforcomparison |