Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture
Mg and its composites are considered attractive candidates for supplying biomedical implantation. Mg-alloys are gaining popularity for biomedical implant applications, particularly bone regeneration because they have characteristics that are like those of natural bone. Simulated body fluid (SBF) is...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-05-01
|
| Series: | Journal of Materials Research and Technology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785422003477 |
| _version_ | 1819174041653608448 |
|---|---|
| author | Huimin Hu Xiaodong Wang Yansheng Huang Zhao Yang Bin Jia Kai Sun Dingjun Hao Yunshan Guo |
| author_facet | Huimin Hu Xiaodong Wang Yansheng Huang Zhao Yang Bin Jia Kai Sun Dingjun Hao Yunshan Guo |
| author_sort | Huimin Hu |
| collection | DOAJ |
| description | Mg and its composites are considered attractive candidates for supplying biomedical implantation. Mg-alloys are gaining popularity for biomedical implant applications, particularly bone regeneration because they have characteristics that are like those of natural bone. Simulated body fluid (SBF) is an electrolyte that is often utilized in vitro corrosion investigations. Using each SBF module individually and in combination, this research evaluates the corrosion effects on the system. pH alterations hasten the degeneration of the organism's pH and it was decided to explore the corrosion of Mg in an SBF. In this study, the effect of pH changes on the corrosion rate of Mg immersed in standard SBF solution was investigated in detail. According to previously published research, the corrosion process of Mg has been substantiated by scanning electron microscopy examinations of damaged surface morphology. In this investigation, pH 7 was determined to be the optimal pH for physiological fluids since it is neutral. To accomplish these aims, researchers examined Mg–2 wt.% Zn–0.5 wt.% Ca (ZC21) alloy pins microstructurally and mechanically, as well as the degradation of the alloy pins and their interactions with the SBF solution. The degradation of bone and its cytocompatibility with other substances. The degradation control of Mg-alloy occurred at a much slower rate than that of Mg alone. Bone cell development on the applied nano alloy is visible on SEM-EDS charts, demonstrating that this alloy is extremely compatible with human bone and that its usage as a stent for bone fracture is highly suggested in this study. |
| first_indexed | 2024-12-22T20:32:40Z |
| format | Article |
| id | doaj.art-fe25838aecaa4abbac66f1fa453ae679 |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-22T20:32:40Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-fe25838aecaa4abbac66f1fa453ae6792022-12-21T18:13:34ZengElsevierJournal of Materials Research and Technology2238-78542022-05-011816691681Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fractureHuimin Hu0Xiaodong Wang1Yansheng Huang2Zhao Yang3Bin Jia4Kai Sun5Dingjun Hao6Yunshan Guo7Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, ChinaDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, ChinaDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, ChinaCore Facility for Protein Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, ChinaDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, ChinaDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, ChinaDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, China; Corresponding author.Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi Province, 710054, China; Corresponding author.Mg and its composites are considered attractive candidates for supplying biomedical implantation. Mg-alloys are gaining popularity for biomedical implant applications, particularly bone regeneration because they have characteristics that are like those of natural bone. Simulated body fluid (SBF) is an electrolyte that is often utilized in vitro corrosion investigations. Using each SBF module individually and in combination, this research evaluates the corrosion effects on the system. pH alterations hasten the degeneration of the organism's pH and it was decided to explore the corrosion of Mg in an SBF. In this study, the effect of pH changes on the corrosion rate of Mg immersed in standard SBF solution was investigated in detail. According to previously published research, the corrosion process of Mg has been substantiated by scanning electron microscopy examinations of damaged surface morphology. In this investigation, pH 7 was determined to be the optimal pH for physiological fluids since it is neutral. To accomplish these aims, researchers examined Mg–2 wt.% Zn–0.5 wt.% Ca (ZC21) alloy pins microstructurally and mechanically, as well as the degradation of the alloy pins and their interactions with the SBF solution. The degradation of bone and its cytocompatibility with other substances. The degradation control of Mg-alloy occurred at a much slower rate than that of Mg alone. Bone cell development on the applied nano alloy is visible on SEM-EDS charts, demonstrating that this alloy is extremely compatible with human bone and that its usage as a stent for bone fracture is highly suggested in this study.http://www.sciencedirect.com/science/article/pii/S2238785422003477Simulated body fluidBiodegradable Mg-alloyElectrochemical techniquesCorrosionSEM-EDSStent for bone fracture |
| spellingShingle | Huimin Hu Xiaodong Wang Yansheng Huang Zhao Yang Bin Jia Kai Sun Dingjun Hao Yunshan Guo Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture Journal of Materials Research and Technology Simulated body fluid Biodegradable Mg-alloy Electrochemical techniques Corrosion SEM-EDS Stent for bone fracture |
| title | Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture |
| title_full | Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture |
| title_fullStr | Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture |
| title_full_unstemmed | Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture |
| title_short | Electrochemical techniques for monitoring the biodegradability of nanocomposite Mg-alloy/HA for repairing bone fracture |
| title_sort | electrochemical techniques for monitoring the biodegradability of nanocomposite mg alloy ha for repairing bone fracture |
| topic | Simulated body fluid Biodegradable Mg-alloy Electrochemical techniques Corrosion SEM-EDS Stent for bone fracture |
| url | http://www.sciencedirect.com/science/article/pii/S2238785422003477 |
| work_keys_str_mv | AT huiminhu electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT xiaodongwang electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT yanshenghuang electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT zhaoyang electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT binjia electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT kaisun electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT dingjunhao electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture AT yunshanguo electrochemicaltechniquesformonitoringthebiodegradabilityofnanocompositemgalloyhaforrepairingbonefracture |