How sex chromosomes get trapped into nonrecombination

Suppression of recombination along the Y chromosome leads to its degeneration, so why does a process with such potentially deleterious consequences arise? In this issue of PLOS Biology, a new model reveals how and why this might be. We know that suppression of recombination leads to degeneration of...

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Bibliographic Details
Main Author: Jos Käfer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295974/?tool=EBI
Description
Summary:Suppression of recombination along the Y chromosome leads to its degeneration, so why does a process with such potentially deleterious consequences arise? In this issue of PLOS Biology, a new model reveals how and why this might be. We know that suppression of recombination leads to degeneration of Y chromosomes, but it has remained difficult to understand how features with such strong negative effects actually arise. This Primer explores a new model published in PLOS Biology that reveals how this could happen.
ISSN:1544-9173
1545-7885