ISCHAEMIA IN THE NEONATE–CASE REPORT

Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no...

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Main Authors: Roger Rodrigues, Gabriel Anacleto, Carolina Mendes, Juliana Varino, André Marinho, Bárbara Pereira, Mário Moreira, Mafalda Correia, Pedro Lima, Óscar Gonçalves
Format: Article
Language:Portuguese
Published: Sociedade Portuguesa de Angiologia e Cirurgia Vascular 2018-06-01
Series:Angiologia e Cirurgia Vascular
Subjects:
Online Access:https://acvjournal.com/index.php/acv/article/view/64
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author Roger Rodrigues
Gabriel Anacleto
Carolina Mendes
Juliana Varino
André Marinho
Bárbara Pereira
Mário Moreira
Mafalda Correia
Pedro Lima
Óscar Gonçalves
author_facet Roger Rodrigues
Gabriel Anacleto
Carolina Mendes
Juliana Varino
André Marinho
Bárbara Pereira
Mário Moreira
Mafalda Correia
Pedro Lima
Óscar Gonçalves
author_sort Roger Rodrigues
collection DOAJ
description Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no large trials comparing different therapies. Objectives: The authors describe the case of a 4-day newborn transferred to the Pediatric Hospital for a gangrene of the lower limb. Results: In this case the member was not salvageable. Treatment with Heparin was performed which is usually effective in cases of neonatal limb ischaemia, but in this case the evolution was not favorable. The diagnosis was late and an amputation of the leg was performed. A multidisciplinary team of surgeons, paediatricians, occupational therapists, physiotherapists, working together provided the best support network and best treatment for this child. Conclusions: Neonatal limb ischaemia is uncommon, but can have devastating consequences on the patient. Successful management is dependent on early recognition, rapid clinical assessment and appropriate therapy. Initial supportive therapy may be appropriate with aggressive interventional treatment reserved for selective cases. Interventional treatment includes thrombolysis using a tissue plasminogen activator which can be catheter directed or systemic, and surgical thrombectomy, particularly if larger vessels such as the abdominal aorta are involved. Strategies for management are still evolving, and there is only a limited pooled experience available for review in the published literature.
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spelling doaj.art-fe2665492b81466886f3ce75d7928eb52023-01-16T09:17:42ZporSociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular1646-706X2183-00962018-06-0114210.48750/acv.64ISCHAEMIA IN THE NEONATE–CASE REPORTRoger RodriguesGabriel AnacletoCarolina MendesJuliana VarinoAndré MarinhoBárbara PereiraMário MoreiraMafalda CorreiaPedro LimaÓscar Gonçalves Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no large trials comparing different therapies. Objectives: The authors describe the case of a 4-day newborn transferred to the Pediatric Hospital for a gangrene of the lower limb. Results: In this case the member was not salvageable. Treatment with Heparin was performed which is usually effective in cases of neonatal limb ischaemia, but in this case the evolution was not favorable. The diagnosis was late and an amputation of the leg was performed. A multidisciplinary team of surgeons, paediatricians, occupational therapists, physiotherapists, working together provided the best support network and best treatment for this child. Conclusions: Neonatal limb ischaemia is uncommon, but can have devastating consequences on the patient. Successful management is dependent on early recognition, rapid clinical assessment and appropriate therapy. Initial supportive therapy may be appropriate with aggressive interventional treatment reserved for selective cases. Interventional treatment includes thrombolysis using a tissue plasminogen activator which can be catheter directed or systemic, and surgical thrombectomy, particularly if larger vessels such as the abdominal aorta are involved. Strategies for management are still evolving, and there is only a limited pooled experience available for review in the published literature. https://acvjournal.com/index.php/acv/article/view/64GangreneLower ExtremityNeonate
spellingShingle Roger Rodrigues
Gabriel Anacleto
Carolina Mendes
Juliana Varino
André Marinho
Bárbara Pereira
Mário Moreira
Mafalda Correia
Pedro Lima
Óscar Gonçalves
ISCHAEMIA IN THE NEONATE–CASE REPORT
Angiologia e Cirurgia Vascular
Gangrene
Lower Extremity
Neonate
title ISCHAEMIA IN THE NEONATE–CASE REPORT
title_full ISCHAEMIA IN THE NEONATE–CASE REPORT
title_fullStr ISCHAEMIA IN THE NEONATE–CASE REPORT
title_full_unstemmed ISCHAEMIA IN THE NEONATE–CASE REPORT
title_short ISCHAEMIA IN THE NEONATE–CASE REPORT
title_sort ischaemia in the neonate case report
topic Gangrene
Lower Extremity
Neonate
url https://acvjournal.com/index.php/acv/article/view/64
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