Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone
N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2010-11-01
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| Series: | Journal of Pharmacy & Pharmaceutical Sciences |
| Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/8257 |
| _version_ | 1797714062583267328 |
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| author | Abolghasem Jouyban Mohammad Amin Abolghasemi Fakhree Ali Shayanfar |
| author_facet | Abolghasem Jouyban Mohammad Amin Abolghasemi Fakhree Ali Shayanfar |
| author_sort | Abolghasem Jouyban |
| collection | DOAJ |
| description | N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent. |
| first_indexed | 2024-03-12T07:46:26Z |
| format | Article |
| id | doaj.art-fe2765a7cb7648e599ad848bbf136d3a |
| institution | Directory Open Access Journal |
| issn | 1482-1826 |
| language | English |
| last_indexed | 2024-03-12T07:46:26Z |
| publishDate | 2010-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Journal of Pharmacy & Pharmaceutical Sciences |
| spelling | doaj.art-fe2765a7cb7648e599ad848bbf136d3a2023-09-02T20:59:30ZengFrontiers Media S.A.Journal of Pharmacy & Pharmaceutical Sciences1482-18262010-11-0113410.18433/J3P306Review of Pharmaceutical Applications of N-Methyl-2-PyrrolidoneAbolghasem Jouyban0Mohammad Amin Abolghasemi Fakhree1Ali Shayanfar2Tabriz University of Medical SciencesTabriz University of Medical SciencesKimia Research InstituteN-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/8257 |
| spellingShingle | Abolghasem Jouyban Mohammad Amin Abolghasemi Fakhree Ali Shayanfar Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone Journal of Pharmacy & Pharmaceutical Sciences |
| title | Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone |
| title_full | Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone |
| title_fullStr | Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone |
| title_full_unstemmed | Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone |
| title_short | Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone |
| title_sort | review of pharmaceutical applications of n methyl 2 pyrrolidone |
| url | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/8257 |
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