STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells

STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells

<p>Abstract</p> <p>Background</p> <p>Signal Transducer and Activator of Transcription 5 A and B (STAT5) are key survival factors in cells of the lymphoid lineage. Identification of novel, tissue-specific STAT5 regulated genes would advance the ability to combat diseases...

Full description

Bibliographic Details
Main Authors:	Mitra Abhisek, Ross Jeremy A, LeBaron Matthew J, Nagy Zsuzsanna S, Rui Hallgeir, Kirken Robert A
Format:	Article
Language:	English
Published:	BMC 2009-08-01
Series:	Molecular Cancer
Online Access:	http://www.molecular-cancer.com/content/8/1/67

Similar Items

Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells.
by: Zsuzsanna S Nagy, et al.
Published: (2013-01-01)

Correction: Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells.
by: Zsuzsanna S. Nagy, et al.
Published: (2013-01-01)

Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer
by: Rui Hallgeir, et al.
Published: (2005-02-01)

JAK–STAT signalling shapes the NF‐κB response in CLL towards venetoclax sensitivity or resistance via Bcl‐XL
by: Marco V. Haselager, et al.
Published: (2023-06-01)

Aberrant Activation of NF-κB Signalling in Aggressive Lymphoid Malignancies
by: Ruth Kennedy, et al.
Published: (2018-10-01)

Selenadiazole Inhibited Adenovirus-Induced Apoptosis through the Oxidative-Damage-Mediated Bcl-2/Stat 3/NF-κB Signaling Pathway
by: Xia Liu, et al.
Published: (2023-10-01)

Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer
by: Wenfei Pan, et al.
Published: (2022-08-01)

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
by: Ekaterini Platanitis, et al.
Published: (2018-11-01)

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues
by: Ajithkumar Vasanthakumar, et al.
Published: (2017-09-01)

Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma.
by: Tiernan J Mulrooney, et al.
Published: (2011-03-01)

Bcl10 Links Saturated Fat Overnutrition with Hepatocellular NF-κB Activation and Insulin Resistance
by: Matthew Van Beek, et al.
Published: (2012-05-01)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
by: Wonhwa Lee, et al.
Published: (2020-01-01)

Expression Of Intracellular Components of the NF-κB Alternative Pathway (NF-κB2, RelB, NIK and Bcl3) is Associated With Clinical Outcome of NSCLC Patients
by: Foteinos-Ioannis D. Dimitrakopoulos, et al.
Published: (2019-10-01)

The pattern of Ki-67 and bcl-2 expression in Lymphoid Malignancies
by: Wang, P.L., et al.
Published: (1997)

The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney.
by: Zach K O'Brown, et al.
Published: (2015-12-01)

Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.
by: Gaurav Swarnkar, et al.
Published: (2014-01-01)

With a little help from a friend – CaN cooperates with Bcl-10 to activate NF-κB
by: Herzel H, et al.
Published: (2009-02-01)

Targeting STAT3 and NF-κB Signaling Pathways in Cancer Prevention and Treatment: The Role of Chalcones
by: Violetta Krajka-Kuźniak, et al.
Published: (2024-03-01)

Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-κB and STAT-1
by: Nayeon Kim, et al.
Published: (2022-09-01)

PIAS Factors from Rainbow Trout Control NF-κB- and STAT-Dependent Gene Expression
by: Fabio Sarais, et al.
Published: (2021-11-01)

Fluoxetine inactivates STAT3/NF-κB signaling and promotes sensitivity to cisplatin in bladder cancer
by: Che-Jui Yang, et al.
Published: (2023-08-01)

NF-κB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
by: Braden C McFarland, et al.
Published: (2013-01-01)

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
by: Maciej Czerkies, et al.
Published: (2018-02-01)

Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages
by: Zahidul Alam, et al.
Published: (2020-06-01)

Regulation of NF-κB- and STAT1-mediated plasmacytoid dendritic cell functions by A20.
by: Pham Ngoc Duy, et al.
Published: (2019-01-01)

Methylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 Activities.
by: Youn Hee Joung, et al.
Published: (2016-01-01)

Constitutively active canonical NF-κB pathway induces severe bone loss in mice.
by: Jesse E Otero, et al.
Published: (2012-01-01)

LTBP2 regulates cisplatin resistance in GC cells via activation of the NF-κB2/BCL3 pathway
by: Jun Wang, et al.
Published: (2024-04-01)

Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells
by: Fuxiao Wang, et al.
Published: (2022-07-01)

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition
by: Arbab, I.A., et al.
Published: (2012)

The anti-apoptosis effect of isovitexin on human keratinocytes by regulating miR-98-5p/Bcl-2/Bcl-xL and MAPKs/NF-κB signaling pathways
by: Xuechun Lv, et al.
Published: (2023-10-01)

Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model
by: Wang, L, et al.
Published: (2019)

Adiponectin Suppresses Metastasis of Nasopharyngeal Carcinoma through Blocking the Activation of NF-κB and STAT3 Signaling
by: Zongmeng Zhang, et al.
Published: (2022-10-01)

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex
by: Sebastian Wienerroither, et al.
Published: (2015-07-01)

Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model.
by: Lihui Wang, et al.
Published: (2019-03-01)

New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors
by: Elena Gabriele, et al.
Published: (2017-01-01)

Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression
by: Maren Feist, et al.
Published: (2018-04-01)

Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3
by: Jing Ma, et al.
Published: (2018-01-01)

NF-κB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury
by: Tatyana Ageeva, et al.
Published: (2024-03-01)

Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways
by: José Esparza-López, et al.
Published: (2019-07-01)