Knockdown of NUPR1 inhibits angiogenesis in lung cancer through IRE1/XBP1 and PERK/eIF2α/ATF4 signaling pathways

Knockdown of NUPR1 inhibits angiogenesis in lung cancer through IRE1/XBP1 and PERK/eIF2α/ATF4 signaling pathways

The stress response molecule nuclear protein‑1 (NUPR1) is essential for the growth of multiple types of human malignant tumor cells. However, the significance of NUPR1 in lung cancer is still not entirely elucidated. Therefore, this study is aimed to explore the function and underlying mechanisms of...

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Bibliographic Details
Main Authors: Wang Lihuai, Wen Jing, Sun Yinhui, Yang Xiao, Ma Yi, Tian Xuefei
Format: Article
Language:English
Published: De Gruyter 2023-10-01
Series:Open Medicine
Subjects:
nupr1
lung cancer
angiogenesis
signaling pathways
Online Access:https://doi.org/10.1515/med-2023-0796

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