In Silico Approaches for the Identification of Aptamer Binding Interactions to <i>Leptospira</i> spp. Cell Surface Proteins

In Silico Approaches for the Identification of Aptamer Binding Interactions to <i>Leptospira</i> spp. Cell Surface Proteins

Aptamers are nucleic acids that can bind with high affinity and specificity to a range of target molecules. However, their functionality relies on their secondary and tertiary structures such that the combination of nucleotides determines their three-dimensional conformation. In this study, the bind...

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Bibliographic Details
Main Authors: Chembie A. Almazar, Marjo V. Mendoza, Windell L. Rivera
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Tropical Medicine and Infectious Disease
Subjects:
<i>Leptospira</i>
in silico
aptamer
molecular docking
binding interactions
Online Access:https://www.mdpi.com/2414-6366/8/2/125

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