Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report
Acquired angioedema with C1 inhibitor deficiency (AAE-C1INH) is a very rare condition of bradykinin-mediated angioedema. One of its major complications is potentially life-threatening, laryngeal edema. We report a 53-year-old woman with AAE-C1INH proposed for an elective broncofibroscopy. The direct...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Brazilian Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0104001421004061 |
| _version_ | 1797786607493840896 |
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| author | Melanie Barata Ana Marques Catarina Tiago Marta Dias-Vaz Nuno Losa Carmen Oliveira |
| author_facet | Melanie Barata Ana Marques Catarina Tiago Marta Dias-Vaz Nuno Losa Carmen Oliveira |
| author_sort | Melanie Barata |
| collection | DOAJ |
| description | Acquired angioedema with C1 inhibitor deficiency (AAE-C1INH) is a very rare condition of bradykinin-mediated angioedema. One of its major complications is potentially life-threatening, laryngeal edema. We report a 53-year-old woman with AAE-C1INH proposed for an elective broncofibroscopy. The direct stimulation caused by broncofibroscopy poses a high risk of angioedema, thus presenting an anesthetic challenge. Due to the risk of death, it is essential to adopt preventive measures. Short-term prophylaxis was performed, and the acute treatment was readily available. A well-structured multidisciplinary periprocedural plan makes it possible to safely approach the airway, in a remote area of the hospital. |
| first_indexed | 2024-03-13T01:11:16Z |
| format | Article |
| id | doaj.art-fe32d50cf1614989b1f722bdde1ada7a |
| institution | Directory Open Access Journal |
| issn | 0104-0014 |
| language | English |
| last_indexed | 2024-03-13T01:11:16Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Anesthesiology |
| spelling | doaj.art-fe32d50cf1614989b1f722bdde1ada7a2023-07-06T04:16:56ZengElsevierBrazilian Journal of Anesthesiology0104-00142023-07-01734500502Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case reportMelanie Barata0Ana Marques1Catarina Tiago2Marta Dias-Vaz3Nuno Losa4Carmen Oliveira5Corresponding author.; Centro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalCentro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalCentro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalCentro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalCentro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalCentro Hospitalar Vila Nova de Gaia/Espinho, Department of Anaesthesiology, Vila Nova de Gaia, PortugalAcquired angioedema with C1 inhibitor deficiency (AAE-C1INH) is a very rare condition of bradykinin-mediated angioedema. One of its major complications is potentially life-threatening, laryngeal edema. We report a 53-year-old woman with AAE-C1INH proposed for an elective broncofibroscopy. The direct stimulation caused by broncofibroscopy poses a high risk of angioedema, thus presenting an anesthetic challenge. Due to the risk of death, it is essential to adopt preventive measures. Short-term prophylaxis was performed, and the acute treatment was readily available. A well-structured multidisciplinary periprocedural plan makes it possible to safely approach the airway, in a remote area of the hospital.http://www.sciencedirect.com/science/article/pii/S0104001421004061AngioedemaC1 Esterase InhibitorAirway ManagementBronchoscopy |
| spellingShingle | Melanie Barata Ana Marques Catarina Tiago Marta Dias-Vaz Nuno Losa Carmen Oliveira Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report Brazilian Journal of Anesthesiology Angioedema C1 Esterase Inhibitor Airway Management Bronchoscopy |
| title | Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report |
| title_full | Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report |
| title_fullStr | Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report |
| title_full_unstemmed | Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report |
| title_short | Anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy: a case report |
| title_sort | anesthetic management of a patient with acquired angioedema submitted to broncofibroscopy a case report |
| topic | Angioedema C1 Esterase Inhibitor Airway Management Bronchoscopy |
| url | http://www.sciencedirect.com/science/article/pii/S0104001421004061 |
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