Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-03-01
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| Series: | Biomarker Insights |
| Online Access: | https://doi.org/10.1177/1177271917695237 |
| _version_ | 1818061034401824768 |
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| author | Maria Vergoulidou |
| author_facet | Maria Vergoulidou |
| author_sort | Maria Vergoulidou |
| collection | DOAJ |
| description | Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges. |
| first_indexed | 2024-12-10T13:41:54Z |
| format | Article |
| id | doaj.art-fe3458b4cc30429d9f094f1a6965e474 |
| institution | Directory Open Access Journal |
| issn | 1177-2719 |
| language | English |
| last_indexed | 2024-12-10T13:41:54Z |
| publishDate | 2017-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Biomarker Insights |
| spelling | doaj.art-fe3458b4cc30429d9f094f1a6965e4742022-12-22T01:46:39ZengSAGE PublishingBiomarker Insights1177-27192017-03-011210.1177/117727191769523710.1177_1177271917695237Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical ChallengeMaria VergoulidouLeptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.https://doi.org/10.1177/1177271917695237 |
| spellingShingle | Maria Vergoulidou Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge Biomarker Insights |
| title | Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge |
| title_full | Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge |
| title_fullStr | Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge |
| title_full_unstemmed | Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge |
| title_short | Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge |
| title_sort | leptomeningeal carcinomatosis in gastric cancer a therapeutical challenge |
| url | https://doi.org/10.1177/1177271917695237 |
| work_keys_str_mv | AT mariavergoulidou leptomeningealcarcinomatosisingastriccanceratherapeuticalchallenge |