Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model
Epineural stitches are a means to avoid tension in a nerve suture. We evaluate this technique, relative to interposed grafts and simple neurorraphy, in a rat model. METHOD: Twenty rats were allocated to four groups. For Group 1, sectioning of the sciatic nerve was performed, a segment 4 mm long disc...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2011-01-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300019&lng=en&tlng=en |
| _version_ | 1818257670756368384 |
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| author | J Bustamante M Socolovsky R S Martins J Emmerich M G Pennini N Lausada L Domitrovic |
| author_facet | J Bustamante M Socolovsky R S Martins J Emmerich M G Pennini N Lausada L Domitrovic |
| author_sort | J Bustamante |
| collection | DOAJ |
| description | Epineural stitches are a means to avoid tension in a nerve suture. We evaluate this technique, relative to interposed grafts and simple neurorraphy, in a rat model. METHOD: Twenty rats were allocated to four groups. For Group 1, sectioning of the sciatic nerve was performed, a segment 4 mm long discarded, and epineural suture with distal anchoring stitches were placed resulting in slight tension neurorraphy. For Group 2, a simple neurorraphy was performed. For Group 3, a 4 mm long graft was employed and Group 4 served as control. Ninety days after, reoperation, latency of motor action potentials recording and axonal counts were performed. Inter-group comparison was done by means of ANOVA and the non-parametric Kruskal-Wallis test. RESULTS: The mean motor latency for the simple suture (2.27±0.77 ms) was lower than for the other two surgical groups, but lower than among controls (1.69±0.56 ms). Similar values were founding in both group 1 (2.66±0.71 ms) and group 3 (2.64±0.6 ms). When fibers diameters were compared a significant difference was identified between groups 2 and 3 (p=0.048). CONCLUSION: Good results can be obtained when suturing a nerve employ with epineural anchoring stitches. However, more studies are needed before extrapolating results to human nerve sutures. |
| first_indexed | 2024-12-12T17:47:21Z |
| format | Article |
| id | doaj.art-fe3515c01ef14ee886fd1f5277aabfdd |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-12T17:47:21Z |
| publishDate | 2011-01-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-fe3515c01ef14ee886fd1f5277aabfdd2022-12-22T00:16:54ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272011-01-01692b36537010.1590/S0004-282X2011000300019S0004-282X2011000300019Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal modelJ Bustamante0M Socolovsky1R S Martins2J Emmerich3M G Pennini4N Lausada5L Domitrovic6Universidad Nacional de La PlataUniversidad de Buenos AiresUniversity of São PauloHospital de Pediatría Sor María LudovicaHospital de Pediatría Sor María LudovicaUniversidad Nacional de La PlataUniversidad de Buenos AiresEpineural stitches are a means to avoid tension in a nerve suture. We evaluate this technique, relative to interposed grafts and simple neurorraphy, in a rat model. METHOD: Twenty rats were allocated to four groups. For Group 1, sectioning of the sciatic nerve was performed, a segment 4 mm long discarded, and epineural suture with distal anchoring stitches were placed resulting in slight tension neurorraphy. For Group 2, a simple neurorraphy was performed. For Group 3, a 4 mm long graft was employed and Group 4 served as control. Ninety days after, reoperation, latency of motor action potentials recording and axonal counts were performed. Inter-group comparison was done by means of ANOVA and the non-parametric Kruskal-Wallis test. RESULTS: The mean motor latency for the simple suture (2.27±0.77 ms) was lower than for the other two surgical groups, but lower than among controls (1.69±0.56 ms). Similar values were founding in both group 1 (2.66±0.71 ms) and group 3 (2.64±0.6 ms). When fibers diameters were compared a significant difference was identified between groups 2 and 3 (p=0.048). CONCLUSION: Good results can be obtained when suturing a nerve employ with epineural anchoring stitches. However, more studies are needed before extrapolating results to human nerve sutures.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300019&lng=en&tlng=enneurorrafiatensãoenxerto autólogosutura nervosanervo periférico |
| spellingShingle | J Bustamante M Socolovsky R S Martins J Emmerich M G Pennini N Lausada L Domitrovic Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model Arquivos de Neuro-Psiquiatria neurorrafia tensão enxerto autólogo sutura nervosa nervo periférico |
| title | Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| title_full | Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| title_fullStr | Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| title_full_unstemmed | Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| title_short | Effects of eliminating tension by means of epineural stitches: a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| title_sort | effects of eliminating tension by means of epineural stitches a comparative electrophysiological and histomorphometrical study using different suture techniques in an animal model |
| topic | neurorrafia tensão enxerto autólogo sutura nervosa nervo periférico |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000300019&lng=en&tlng=en |
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