Case of Carbapenem-Resistant Salmonella Typhi Infection, Pakistan, 2022

Case of Carbapenem-Resistant Salmonella Typhi Infection, Pakistan, 2022

Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous mero...

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Bibliographic Details
Main Authors: Summiya Nizamuddin, Ejaz Ahmed Khan, Marie Anne Chattaway, Gauri Godbole
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2023-11-01
Series:Emerging Infectious Diseases
Subjects:
Salmonella Typhi
Salmonella enteria serovar Typhi
therapy
diagnosis
antimicrobial resistance
carbapenem resistance
Online Access:https://wwwnc.cdc.gov/eid/article/29/11/23-0499_article
Description
Summary:Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous meropenem and colistin was successful. Carbapenem-resistant Salmonella Typhi emergence will hinder treatment.
ISSN:1080-6040
1080-6059

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