Screening for retinopathy of prematurity in North China
Abstract Purpose To analyze the incidence and severity of retinopathy of prematurity (ROP) in north China, and to evaluate the effectiveness of different ROP screening criteria. Patients and methods The screening data of premature infants were collected from 2016 to 2021. The severity of ROP was gra...
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02470-3 |
| _version_ | 1818252978404982784 |
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| author | Li Li Yanlin Gao Wei Chen Mei Han |
| author_facet | Li Li Yanlin Gao Wei Chen Mei Han |
| author_sort | Li Li |
| collection | DOAJ |
| description | Abstract Purpose To analyze the incidence and severity of retinopathy of prematurity (ROP) in north China, and to evaluate the effectiveness of different ROP screening criteria. Patients and methods The screening data of premature infants were collected from 2016 to 2021. The severity of ROP was graded according to the International Classification of Retinopathy of Prematurity (2005). And the treatment for ROP followed the Early Treatment for Retinopathy of Prematurity Cooperative Group. The effects of gestational age (GA) and birth weight (BW) on the incidence and severity of ROP were evaluated. The screening data were also analyzed using different ROP screening guidelines. Results A total of 4069 infants underwent ROP screening, and 728 infants (17.9%) were diagnosed with ROP. Of those, 78 infants (1.9%) received treatments. Gestational age and BW showed significant differences between infants with and without ROP (29.1 ± 2.1w vs. 32.9 ± 2.6w, p < 0.001; 1362.7 ± 427.3 g vs. 1751.9 ± 509.4 g, p < 0.001; respectively). Fifty-six infants (7.69%), 188 infants (25.82%), and 104 infants (14.29%) in all infants with ROP would have been missed according to the China, USA, and UK screening guidelines respectively. If GA ≤ 33 weeks and/or BW ≤ 2100 g were considered as screening criteria, only one infant (0.14%) with critical systemic illness was missed diagnosed with severe ROP. Conclusion Gestational age and BW are major risk factors for the incidence and severity of ROP. And the incidence and treatment rate of ROP in Tianjin is similar to that reported in the other regions of China. Modified ROP screening criteria were considered to be more effective in Tianjin. |
| first_indexed | 2024-12-12T16:32:46Z |
| format | Article |
| id | doaj.art-fe3c23b8b6c84315a75ef86f44249b21 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-12T16:32:46Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-fe3c23b8b6c84315a75ef86f44249b212022-12-22T00:18:45ZengBMCBMC Ophthalmology1471-24152022-06-012211810.1186/s12886-022-02470-3Screening for retinopathy of prematurity in North ChinaLi Li0Yanlin Gao1Wei Chen2Mei Han3Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Nankai University Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical UniversityTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Nankai University Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical UniversityTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Nankai University Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical UniversityTianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Nankai University Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical UniversityAbstract Purpose To analyze the incidence and severity of retinopathy of prematurity (ROP) in north China, and to evaluate the effectiveness of different ROP screening criteria. Patients and methods The screening data of premature infants were collected from 2016 to 2021. The severity of ROP was graded according to the International Classification of Retinopathy of Prematurity (2005). And the treatment for ROP followed the Early Treatment for Retinopathy of Prematurity Cooperative Group. The effects of gestational age (GA) and birth weight (BW) on the incidence and severity of ROP were evaluated. The screening data were also analyzed using different ROP screening guidelines. Results A total of 4069 infants underwent ROP screening, and 728 infants (17.9%) were diagnosed with ROP. Of those, 78 infants (1.9%) received treatments. Gestational age and BW showed significant differences between infants with and without ROP (29.1 ± 2.1w vs. 32.9 ± 2.6w, p < 0.001; 1362.7 ± 427.3 g vs. 1751.9 ± 509.4 g, p < 0.001; respectively). Fifty-six infants (7.69%), 188 infants (25.82%), and 104 infants (14.29%) in all infants with ROP would have been missed according to the China, USA, and UK screening guidelines respectively. If GA ≤ 33 weeks and/or BW ≤ 2100 g were considered as screening criteria, only one infant (0.14%) with critical systemic illness was missed diagnosed with severe ROP. Conclusion Gestational age and BW are major risk factors for the incidence and severity of ROP. And the incidence and treatment rate of ROP in Tianjin is similar to that reported in the other regions of China. Modified ROP screening criteria were considered to be more effective in Tianjin.https://doi.org/10.1186/s12886-022-02470-3Retinopathy of prematurityGestational ageBirth weightScreening criteria |
| spellingShingle | Li Li Yanlin Gao Wei Chen Mei Han Screening for retinopathy of prematurity in North China BMC Ophthalmology Retinopathy of prematurity Gestational age Birth weight Screening criteria |
| title | Screening for retinopathy of prematurity in North China |
| title_full | Screening for retinopathy of prematurity in North China |
| title_fullStr | Screening for retinopathy of prematurity in North China |
| title_full_unstemmed | Screening for retinopathy of prematurity in North China |
| title_short | Screening for retinopathy of prematurity in North China |
| title_sort | screening for retinopathy of prematurity in north china |
| topic | Retinopathy of prematurity Gestational age Birth weight Screening criteria |
| url | https://doi.org/10.1186/s12886-022-02470-3 |
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