Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring.
<h4>Background</h4>Atrial fibrillation (AF) is the most common arrhythmia and often recurs despite catheter ablation. The recurrence of AF is often underdiagnosed by standard 24-hour electrocardiogram (ECG) because of its transient and silent nature. A garment-style ECG with a highly con...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0281818 |
| _version_ | 1797848215043702784 |
|---|---|
| author | Takeshi Machino Kazutaka Aonuma Kazushi Maruo Yuki Komatsu Hiro Yamasaki Miyako Igarashi Akihiko Nogami Masaki Ieda |
| author_facet | Takeshi Machino Kazutaka Aonuma Kazushi Maruo Yuki Komatsu Hiro Yamasaki Miyako Igarashi Akihiko Nogami Masaki Ieda |
| author_sort | Takeshi Machino |
| collection | DOAJ |
| description | <h4>Background</h4>Atrial fibrillation (AF) is the most common arrhythmia and often recurs despite catheter ablation. The recurrence of AF is often underdiagnosed by standard 24-hour electrocardiogram (ECG) because of its transient and silent nature. A garment-style ECG with a highly conductive textile electrode made of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate)(PEDOTPSS) and nanofiber (Garment ECG) has been developed that can provide longer-term continuous monitoring. This study investigated whether 2-week Garment ECG can reveal instances of AF recurrence in patients who are diagnosed as remaining in sinus rhythm by 24-hour Holter ECG.<h4>Methods</h4>The open-label randomized crossover study enrolled 67 patients (63.1±10.6 years old, 53 men) who had undergone initial AF ablation. Three months after ablation, patients were randomly assigned to group 1 (n = 35), 2-week Garment ECG followed by 24-hour Holter ECG, or group 2 (n = 32), 24-hour Holter ECG followed by 2-week Garment ECG. The detection of AF recurrence was compared between the two devices.<h4>Results</h4>The Garment ECG showed AF recurrence in 12 patients (18%) compared to 4 patients for the Holter ECG (6%, p = 0.008). The ECG acquisition rate was higher for Holter ECG than for Garment ECG (100.0% [interquartile range 100.0-100.0%] versus 82.4% [71.1-91.0%], p<0.001), but the Garment ECG provided longer total analysis time (11.0 days [9.0-12.2 days] for Garment; 1.0 day [1.0-1.0 day] for Holter, p<0.001).<h4>Conclusions</h4>Despite the lower ECG acquisition rate, the 2-week Garment ECG revealed instances of AF recurrence after ablation in patients who were underdiagnosed by 24-hour Holter ECG.<h4>Trial registration</h4>Clinical Trial Registration: URL: https://jrct.niph.go.jp/en-latest-detail/jRCTs032180018 Unique Identifier: jRCTs032180018. |
| first_indexed | 2024-04-09T18:23:51Z |
| format | Article |
| id | doaj.art-fe3fd582081e4b12adaaac52da9cee6c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-09T18:23:51Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-fe3fd582081e4b12adaaac52da9cee6c2023-04-12T05:31:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01182e028181810.1371/journal.pone.0281818Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring.Takeshi MachinoKazutaka AonumaKazushi MaruoYuki KomatsuHiro YamasakiMiyako IgarashiAkihiko NogamiMasaki Ieda<h4>Background</h4>Atrial fibrillation (AF) is the most common arrhythmia and often recurs despite catheter ablation. The recurrence of AF is often underdiagnosed by standard 24-hour electrocardiogram (ECG) because of its transient and silent nature. A garment-style ECG with a highly conductive textile electrode made of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate)(PEDOTPSS) and nanofiber (Garment ECG) has been developed that can provide longer-term continuous monitoring. This study investigated whether 2-week Garment ECG can reveal instances of AF recurrence in patients who are diagnosed as remaining in sinus rhythm by 24-hour Holter ECG.<h4>Methods</h4>The open-label randomized crossover study enrolled 67 patients (63.1±10.6 years old, 53 men) who had undergone initial AF ablation. Three months after ablation, patients were randomly assigned to group 1 (n = 35), 2-week Garment ECG followed by 24-hour Holter ECG, or group 2 (n = 32), 24-hour Holter ECG followed by 2-week Garment ECG. The detection of AF recurrence was compared between the two devices.<h4>Results</h4>The Garment ECG showed AF recurrence in 12 patients (18%) compared to 4 patients for the Holter ECG (6%, p = 0.008). The ECG acquisition rate was higher for Holter ECG than for Garment ECG (100.0% [interquartile range 100.0-100.0%] versus 82.4% [71.1-91.0%], p<0.001), but the Garment ECG provided longer total analysis time (11.0 days [9.0-12.2 days] for Garment; 1.0 day [1.0-1.0 day] for Holter, p<0.001).<h4>Conclusions</h4>Despite the lower ECG acquisition rate, the 2-week Garment ECG revealed instances of AF recurrence after ablation in patients who were underdiagnosed by 24-hour Holter ECG.<h4>Trial registration</h4>Clinical Trial Registration: URL: https://jrct.niph.go.jp/en-latest-detail/jRCTs032180018 Unique Identifier: jRCTs032180018.https://doi.org/10.1371/journal.pone.0281818 |
| spellingShingle | Takeshi Machino Kazutaka Aonuma Kazushi Maruo Yuki Komatsu Hiro Yamasaki Miyako Igarashi Akihiko Nogami Masaki Ieda Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. PLoS ONE |
| title | Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. |
| title_full | Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. |
| title_fullStr | Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. |
| title_full_unstemmed | Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. |
| title_short | Randomized crossover trial of 2-week Garment electrocardiogram with dry textile electrode to reveal instances of post-ablation recurrence of atrial fibrillation underdiagnosed during 24-hour Holter monitoring. |
| title_sort | randomized crossover trial of 2 week garment electrocardiogram with dry textile electrode to reveal instances of post ablation recurrence of atrial fibrillation underdiagnosed during 24 hour holter monitoring |
| url | https://doi.org/10.1371/journal.pone.0281818 |
| work_keys_str_mv | AT takeshimachino randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT kazutakaaonuma randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT kazushimaruo randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT yukikomatsu randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT hiroyamasaki randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT miyakoigarashi randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT akihikonogami randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring AT masakiieda randomizedcrossovertrialof2weekgarmentelectrocardiogramwithdrytextileelectrodetorevealinstancesofpostablationrecurrenceofatrialfibrillationunderdiagnosedduring24hourholtermonitoring |