Novel implications of a strictly monomorphic (GCC) repeat in the human PRKACB gene
Abstract PRKACB (Protein Kinase CAMP-Activated Catalytic Subunit Beta) is predominantly expressed in the brain, and regulation of this gene links to neuroprotective effects against tau and Aβ-induced toxicity. Here we studied a (GCC)-repeat spanning the core promoter and 5′ UTR of this gene in 300 h...
Main Authors: | Safoura Khamse, Zahra Jafarian, Ali Bozorgmehr, Mostafa Tavakoli, Hossein Afshar, Maryam Keshavarz, Razieh Moayedi, Mina Ohadi |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-10-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-99932-3 |
Similar Items
-
A (GCC) repeat in SBF1 reveals a novel biological phenomenon in human and links to late onset neurocognitive disorder
by: Safoura Khamse, et al.
Published: (2022-09-01) -
Natural selection at the RASGEF1C (GGC) repeat in human and divergent genotypes in late-onset neurocognitive disorder
by: Z. Jafarian, et al.
Published: (2021-09-01) -
Dyads of GGC and GCC form hotspot colonies that coincide with the evolution of human and other great apes
by: M. Arabfard, et al.
Published: (2024-02-01) -
CircRAD18 Accelerates the Progression of Acute Myeloid Leukemia by Modulation of miR-206/PRKACB Axis
by: Wang Y, et al.
Published: (2020-10-01) -
Sandpile monomorphisms and limits
by: Lang, Moritz, et al.
Published: (2022-04-01)