Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation
<i>Objective.</i> To assess the effects of neurostimulation (i.e., neuromuscular electrical stimulation (NMES) and pharyngeal electrical stimulation (PES)) in people with oropharyngeal dysphagia (OD). <i>Methods.</i> Systematic literature searches were conducted to retrieve r...
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| Format: | Article |
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MDPI AG
2022-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/3/776 |
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| author | Renée Speyer Anna-Liisa Sutt Liza Bergström Shaheen Hamdy Bas Joris Heijnen Lianne Remijn Sarah Wilkes-Gillan Reinie Cordier |
| author_facet | Renée Speyer Anna-Liisa Sutt Liza Bergström Shaheen Hamdy Bas Joris Heijnen Lianne Remijn Sarah Wilkes-Gillan Reinie Cordier |
| author_sort | Renée Speyer |
| collection | DOAJ |
| description | <i>Objective.</i> To assess the effects of neurostimulation (i.e., neuromuscular electrical stimulation (NMES) and pharyngeal electrical stimulation (PES)) in people with oropharyngeal dysphagia (OD). <i>Methods.</i> Systematic literature searches were conducted to retrieve randomised controlled trials in four electronic databases (CINAHL, Embase, PsycINFO, and PubMed). The methodological quality of included studies was assessed using the Revised Cochrane risk-of-bias tool for randomised trials (RoB 2). <i>Results.</i> In total, 42 studies reporting on peripheral neurostimulation were included: 30 studies on NMES, eight studies on PES, and four studies on combined neurostimulation interventions. When conducting meta analyses, significant, large and significant, moderate pre-post treatment effects were found for NMES (11 studies) and PES (five studies), respectively. Between-group analyses showed small effect sizes in favour of NMES, but no significant effects for PES. <i>Conclusions.</i> NMES may have more promising effects compared to PES. However, NMES studies showed high heterogeneity in protocols and experimental variables, the presence of potential moderators, and inconsistent reporting of methodology. Therefore, only conservative generalisations and interpretation of meta-analyses could be made. To facilitate comparisons of studies and determine intervention effects, there is a need for more randomised controlled trials with larger population sizes, and greater standardisation of protocols and guidelines for reporting. |
| first_indexed | 2024-03-09T23:40:30Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:40:30Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-fe49fc27fd014a7bb6d8160884eeddf62023-11-23T16:53:49ZengMDPI AGJournal of Clinical Medicine2077-03832022-01-0111377610.3390/jcm11030776Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical StimulationRenée Speyer0Anna-Liisa Sutt1Liza Bergström2Shaheen Hamdy3Bas Joris Heijnen4Lianne Remijn5Sarah Wilkes-Gillan6Reinie Cordier7Department Special Needs Education, Faculty of Educational Sciences, University of Oslo, 0318 Oslo, NorwayCritical Care Research Group, The Prince Charles Hospital, Brisbane, QLD 4032, AustraliaRemeo Stockholm, 128 64 Stockholm, SwedenGI Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UKDepartment of Otorhinolaryngology and Head and Neck Surgery, Leiden University Medical Centre, 1233 ZA Leiden, The NetherlandsSchool of Allied Health, HAN University of Applied Sciences, 6525 EN Nijmegen, The NetherlandsDiscipline of Occupational Therapy, Sydney School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, AustraliaCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, WA 6102, Australia<i>Objective.</i> To assess the effects of neurostimulation (i.e., neuromuscular electrical stimulation (NMES) and pharyngeal electrical stimulation (PES)) in people with oropharyngeal dysphagia (OD). <i>Methods.</i> Systematic literature searches were conducted to retrieve randomised controlled trials in four electronic databases (CINAHL, Embase, PsycINFO, and PubMed). The methodological quality of included studies was assessed using the Revised Cochrane risk-of-bias tool for randomised trials (RoB 2). <i>Results.</i> In total, 42 studies reporting on peripheral neurostimulation were included: 30 studies on NMES, eight studies on PES, and four studies on combined neurostimulation interventions. When conducting meta analyses, significant, large and significant, moderate pre-post treatment effects were found for NMES (11 studies) and PES (five studies), respectively. Between-group analyses showed small effect sizes in favour of NMES, but no significant effects for PES. <i>Conclusions.</i> NMES may have more promising effects compared to PES. However, NMES studies showed high heterogeneity in protocols and experimental variables, the presence of potential moderators, and inconsistent reporting of methodology. Therefore, only conservative generalisations and interpretation of meta-analyses could be made. To facilitate comparisons of studies and determine intervention effects, there is a need for more randomised controlled trials with larger population sizes, and greater standardisation of protocols and guidelines for reporting.https://www.mdpi.com/2077-0383/11/3/776deglutitionswallowing disordersRCTinterventionneuromuscular electrical stimulationpharyngeal electrical stimulation |
| spellingShingle | Renée Speyer Anna-Liisa Sutt Liza Bergström Shaheen Hamdy Bas Joris Heijnen Lianne Remijn Sarah Wilkes-Gillan Reinie Cordier Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation Journal of Clinical Medicine deglutition swallowing disorders RCT intervention neuromuscular electrical stimulation pharyngeal electrical stimulation |
| title | Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation |
| title_full | Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation |
| title_fullStr | Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation |
| title_full_unstemmed | Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation |
| title_short | Neurostimulation in People with Oropharyngeal Dysphagia: A Systematic Review and Meta-Analyses of Randomised Controlled Trials—Part I: Pharyngeal and Neuromuscular Electrical Stimulation |
| title_sort | neurostimulation in people with oropharyngeal dysphagia a systematic review and meta analyses of randomised controlled trials part i pharyngeal and neuromuscular electrical stimulation |
| topic | deglutition swallowing disorders RCT intervention neuromuscular electrical stimulation pharyngeal electrical stimulation |
| url | https://www.mdpi.com/2077-0383/11/3/776 |
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