EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6
Chronic periodontitis is a multifactorial disease that is characterized by attachment loss and loss of alveolar bone. Periodontal pathogens from the subgingival microbiota are suggested as a major etiological factor for the periodontitis. The host inflammatory response against bacteria and their vir...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Peytchinski Publishing
2016-08-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | http://www.journal-imab-bg.org/issues-2016/issue3/JofIMAB_2016-22-3p1257-1260.pdf |
| _version_ | 1819150867609157632 |
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| author | Antoaneta Mlachkova Velitchka Dosseva-Panova Christina Popova Maya Kicheva |
| author_facet | Antoaneta Mlachkova Velitchka Dosseva-Panova Christina Popova Maya Kicheva |
| author_sort | Antoaneta Mlachkova |
| collection | DOAJ |
| description | Chronic periodontitis is a multifactorial disease that is characterized by attachment loss and loss of alveolar bone. Periodontal pathogens from the subgingival microbiota are suggested as a major etiological factor for the periodontitis. The host inflammatory response against bacteria and their virulence factors underlies the current understanding of the pathogenesis of chronic periodontitis. The destructive immune response was shown to be associated with an extremely increased production of inflammatory cytokines in periodontal tissues. The expression of several cytokines likeIL-1β and IL-6 is responsible for alveolar bone resorption, and loss of connective tissue attachment in chronic periodontitis.
Authors reported a reduction in the levels of inflammatory cytokines after successful periodontal therapy. Measuring the levels of inflammatory factors may be diagnostic approach to assess the effectiveness of the therapy of periodontitis. |
| first_indexed | 2024-12-22T14:24:20Z |
| format | Article |
| id | doaj.art-fe52d3b3f8de4a54b8a8e8e7d85411dd |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-12-22T14:24:20Z |
| publishDate | 2016-08-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-fe52d3b3f8de4a54b8a8e8e7d85411dd2022-12-21T18:22:55ZengPeytchinski PublishingJournal of IMAB1312-773X2016-08-012231257126010.5272/jimab.2016223.1257EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6Antoaneta Mlachkova0Velitchka Dosseva-Panova1Christina Popova2Maya Kicheva3Department of Periodontology, Faculty of Dental Medicine, Medical University of Sofia, Bulgaria,Department of Periodontology, Faculty of Dental Medicine, Medical University of Sofia, Bulgaria,Department of Periodontology, Faculty of Dental Medicine, Medical University of Sofia, Bulgaria,PhD, biochemist, Progene Ltd., Sofia, Bulgaria.Chronic periodontitis is a multifactorial disease that is characterized by attachment loss and loss of alveolar bone. Periodontal pathogens from the subgingival microbiota are suggested as a major etiological factor for the periodontitis. The host inflammatory response against bacteria and their virulence factors underlies the current understanding of the pathogenesis of chronic periodontitis. The destructive immune response was shown to be associated with an extremely increased production of inflammatory cytokines in periodontal tissues. The expression of several cytokines likeIL-1β and IL-6 is responsible for alveolar bone resorption, and loss of connective tissue attachment in chronic periodontitis. Authors reported a reduction in the levels of inflammatory cytokines after successful periodontal therapy. Measuring the levels of inflammatory factors may be diagnostic approach to assess the effectiveness of the therapy of periodontitis.http://www.journal-imab-bg.org/issues-2016/issue3/JofIMAB_2016-22-3p1257-1260.pdfchronic periodontitiscytokinesIL-1βIL-6periodontal therapyperiodontal diagnosis |
| spellingShingle | Antoaneta Mlachkova Velitchka Dosseva-Panova Christina Popova Maya Kicheva EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 Journal of IMAB chronic periodontitis cytokines IL-1β IL-6 periodontal therapy periodontal diagnosis |
| title | EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 |
| title_full | EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 |
| title_fullStr | EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 |
| title_full_unstemmed | EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 |
| title_short | EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY BY GINGIVAL EXPRESSION OF IL-1β AND IL-6 |
| title_sort | effectiveness of non surgical periodontal therapy by gingival expression of il 1β and il 6 |
| topic | chronic periodontitis cytokines IL-1β IL-6 periodontal therapy periodontal diagnosis |
| url | http://www.journal-imab-bg.org/issues-2016/issue3/JofIMAB_2016-22-3p1257-1260.pdf |
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