Risk factors of cognitive impairment post-ischemic stroke
Abstract Background Stroke is still remarked as one of the major ailments in Indonesia. Cognitive impairment occurs frequently after stroke events and its predictors are needed to identify patients with a high risk of cognitive impairment. However, the researches done in Indonesia still vary in resu...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023-04-01
|
| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41983-023-00654-2 |
| _version_ | 1797836588856639488 |
|---|---|
| author | Nunki Puspita Utomo Rizaldy Taslim Pinzon |
| author_facet | Nunki Puspita Utomo Rizaldy Taslim Pinzon |
| author_sort | Nunki Puspita Utomo |
| collection | DOAJ |
| description | Abstract Background Stroke is still remarked as one of the major ailments in Indonesia. Cognitive impairment occurs frequently after stroke events and its predictors are needed to identify patients with a high risk of cognitive impairment. However, the researches done in Indonesia still vary in results. This retrospective cohort study evaluated 236 ischemic stroke patients in Bethesda Hospital Yogyakarta from January–November 2020 through medical records. Cognitive impairment was measured by MMSE and CDT, defined as MMSE score $$\le$$ ≤ 20 for patients with the educational attainment of 1–6 years; $$\le$$ ≤ 24 for the educational attainment of > 6 years and/ or CDT < 4. All data were analyzed with univariate test and Chi-square test, followed by logistic regression. Results Of 236 subjects, the frequency of cognitive impairment was 67.4% and the risk factors are age > 80 years old (RR: 1,545; CI 0.136–17.542; p: 0.026), educational attainment ≤ 6 years (RR: 20.016; CI 1.951–222.120; p: 0.012), temporal (RR: 4.238; CI 2.266–7.926; p: 0.007) or multiple site lesion location (RR: 7.522; CI: 3.522–17.532; p: 0.047) and multiple (> 1) lesions (RR: 1,819; CI 0.822–4.022; p: 0.040). Conclusions The prevalence of post-stroke cognitive impairment is high, affecting up to 2 out of 3 people in this study. The risk factors of post-stroke cognitive impairment are age > 80 years, educational attainment $$\le$$ ≤ 6 years, temporal or multiple site lesion, and > 1 lesion. Strict stroke prevention strategies are needed to halt the development of post-stroke cognitive impairment. |
| first_indexed | 2024-04-09T15:12:26Z |
| format | Article |
| id | doaj.art-fe5372673b1d4cefbb4e379a031bdd5b |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-04-09T15:12:26Z |
| publishDate | 2023-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-fe5372673b1d4cefbb4e379a031bdd5b2023-04-30T11:10:43ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292023-04-015911610.1186/s41983-023-00654-2Risk factors of cognitive impairment post-ischemic strokeNunki Puspita Utomo0Rizaldy Taslim Pinzon1Faculty of Medicine, Duta Wacana Christian UniversityFaculty of Medicine, Duta Wacana Christian UniversityAbstract Background Stroke is still remarked as one of the major ailments in Indonesia. Cognitive impairment occurs frequently after stroke events and its predictors are needed to identify patients with a high risk of cognitive impairment. However, the researches done in Indonesia still vary in results. This retrospective cohort study evaluated 236 ischemic stroke patients in Bethesda Hospital Yogyakarta from January–November 2020 through medical records. Cognitive impairment was measured by MMSE and CDT, defined as MMSE score $$\le$$ ≤ 20 for patients with the educational attainment of 1–6 years; $$\le$$ ≤ 24 for the educational attainment of > 6 years and/ or CDT < 4. All data were analyzed with univariate test and Chi-square test, followed by logistic regression. Results Of 236 subjects, the frequency of cognitive impairment was 67.4% and the risk factors are age > 80 years old (RR: 1,545; CI 0.136–17.542; p: 0.026), educational attainment ≤ 6 years (RR: 20.016; CI 1.951–222.120; p: 0.012), temporal (RR: 4.238; CI 2.266–7.926; p: 0.007) or multiple site lesion location (RR: 7.522; CI: 3.522–17.532; p: 0.047) and multiple (> 1) lesions (RR: 1,819; CI 0.822–4.022; p: 0.040). Conclusions The prevalence of post-stroke cognitive impairment is high, affecting up to 2 out of 3 people in this study. The risk factors of post-stroke cognitive impairment are age > 80 years, educational attainment $$\le$$ ≤ 6 years, temporal or multiple site lesion, and > 1 lesion. Strict stroke prevention strategies are needed to halt the development of post-stroke cognitive impairment.https://doi.org/10.1186/s41983-023-00654-2Cognitive impairmentIschemic strokeRisk factors |
| spellingShingle | Nunki Puspita Utomo Rizaldy Taslim Pinzon Risk factors of cognitive impairment post-ischemic stroke The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Cognitive impairment Ischemic stroke Risk factors |
| title | Risk factors of cognitive impairment post-ischemic stroke |
| title_full | Risk factors of cognitive impairment post-ischemic stroke |
| title_fullStr | Risk factors of cognitive impairment post-ischemic stroke |
| title_full_unstemmed | Risk factors of cognitive impairment post-ischemic stroke |
| title_short | Risk factors of cognitive impairment post-ischemic stroke |
| title_sort | risk factors of cognitive impairment post ischemic stroke |
| topic | Cognitive impairment Ischemic stroke Risk factors |
| url | https://doi.org/10.1186/s41983-023-00654-2 |
| work_keys_str_mv | AT nunkipuspitautomo riskfactorsofcognitiveimpairmentpostischemicstroke AT rizaldytaslimpinzon riskfactorsofcognitiveimpairmentpostischemicstroke |