Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke

Aim. To investigate the effects of perindopril and indapamide combination (Noliprel® forte) on circadian blood pressure profile (CBPP) and cerebral hemodynamics (CH) among patients in late post-ischemic stroke (IS) period. Material and methods. In total, 30 patients with arterial hypertension (AH) w...

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Main Authors: N. P. Shilkina, I. E. Yunonin, N. V. Pizova, N. V. Sokolova, E. V. Volkova, E. V. Grigoryeva
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2007-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1231
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author N. P. Shilkina
I. E. Yunonin
N. V. Pizova
N. V. Sokolova
E. V. Volkova
E. V. Grigoryeva
author_facet N. P. Shilkina
I. E. Yunonin
N. V. Pizova
N. V. Sokolova
E. V. Volkova
E. V. Grigoryeva
author_sort N. P. Shilkina
collection DOAJ
description Aim. To investigate the effects of perindopril and indapamide combination (Noliprel® forte) on circadian blood pressure profile (CBPP) and cerebral hemodynamics (CH) among patients in late post-ischemic stroke (IS) period. Material and methods. In total, 30 patients with arterial hypertension (AH) were examined, including 15 with previous IS. At baseline and 21 days later, neurological status and cognitive function assessment, experimental psychological examination, 24-hour BP monitoring, rheoencephalography, brachial and cerebral Doppler ultrasoundwere performed. Both groups received Noliprel® forte, 1-2 tablets, once per day. Results. Stroke in anamnesis substantially influenced CH and CBPP parameters in AH patients. Conclusion. Noliprel® forte is an effective antihypertensive medication, not only reducing BP, but also improving CH and cognitive function in patients with AH and stroke.
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spelling doaj.art-fe54c255435c44aa8a377ee478d83ed32024-10-17T12:21:25Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-06-0163510942Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and strokeN. P. Shilkina0I. E. Yunonin1N. V. Pizova2N. V. Sokolova3E. V. Volkova4E. V. Grigoryeva5Yaroslavl State Medical Academy, YaroslavlYaroslavl State Medical Academy, YaroslavlYaroslavl State Medical Academy, YaroslavlYaroslavl State Medical Academy, YaroslavlYaroslavl State Medical Academy, YaroslavlYaroslavl State Medical Academy, YaroslavlAim. To investigate the effects of perindopril and indapamide combination (Noliprel® forte) on circadian blood pressure profile (CBPP) and cerebral hemodynamics (CH) among patients in late post-ischemic stroke (IS) period. Material and methods. In total, 30 patients with arterial hypertension (AH) were examined, including 15 with previous IS. At baseline and 21 days later, neurological status and cognitive function assessment, experimental psychological examination, 24-hour BP monitoring, rheoencephalography, brachial and cerebral Doppler ultrasoundwere performed. Both groups received Noliprel® forte, 1-2 tablets, once per day. Results. Stroke in anamnesis substantially influenced CH and CBPP parameters in AH patients. Conclusion. Noliprel® forte is an effective antihypertensive medication, not only reducing BP, but also improving CH and cognitive function in patients with AH and stroke.https://cardiovascular.elpub.ru/jour/article/view/1231arterial hypertensionischemic stroke24-hour blood pressure monitoringnoliprel® forte
spellingShingle N. P. Shilkina
I. E. Yunonin
N. V. Pizova
N. V. Sokolova
E. V. Volkova
E. V. Grigoryeva
Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
Кардиоваскулярная терапия и профилактика
arterial hypertension
ischemic stroke
24-hour blood pressure monitoring
noliprel® forte
title Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
title_full Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
title_fullStr Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
title_full_unstemmed Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
title_short Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
title_sort perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
topic arterial hypertension
ischemic stroke
24-hour blood pressure monitoring
noliprel® forte
url https://cardiovascular.elpub.ru/jour/article/view/1231
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