Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission
Introduction Degenerative changes in the otolithic organs have been theorized to be caused by the mechanical obstruction to endolymphatic flow, possibly resulting in endolymphatic hydrops (ELH). Otolin-1 is an otoconial matrix protein that crosses the blood labyrinth barrier and has been...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações Ltda.
2023-07-01
|
| Series: | International Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749390 |
| _version_ | 1827877058804449280 |
|---|---|
| author | Anup Singh Harsha Yadav Hitesh Verma Kapil Sikka Ransi Ann Abraham David Victor Kumar Irugu |
| author_facet | Anup Singh Harsha Yadav Hitesh Verma Kapil Sikka Ransi Ann Abraham David Victor Kumar Irugu |
| author_sort | Anup Singh |
| collection | DOAJ |
| description |
Introduction Degenerative changes in the otolithic organs have been theorized to be caused by the mechanical obstruction to endolymphatic flow, possibly resulting in endolymphatic hydrops (ELH). Otolin-1 is an otoconial matrix protein that crosses the blood labyrinth barrier and has been found in the serum of healthy and diseased patients. |
| first_indexed | 2024-03-12T17:31:09Z |
| format | Article |
| id | doaj.art-fe55be67939c4d7c84859560ed3921cd |
| institution | Directory Open Access Journal |
| issn | 1809-9777 1809-4864 |
| language | English |
| last_indexed | 2024-03-12T17:31:09Z |
| publishDate | 2023-07-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | International Archives of Otorhinolaryngology |
| spelling | doaj.art-fe55be67939c4d7c84859560ed3921cd2023-08-04T22:39:21ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642023-07-012703e440e44410.1055/s-0042-1749390Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in RemissionAnup Singh0https://orcid.org/0000-0001-9893-7106Harsha Yadav1https://orcid.org/0000-0002-0056-9518Hitesh Verma2https://orcid.org/0000-0001-7905-3073Kapil Sikka3https://orcid.org/0000-0002-3457-4518Ransi Ann Abraham4https://orcid.org/0000-0003-1954-3112David Victor Kumar Irugu5https://orcid.org/0000-0002-1732-6504Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi, India.Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India. Introduction Degenerative changes in the otolithic organs have been theorized to be caused by the mechanical obstruction to endolymphatic flow, possibly resulting in endolymphatic hydrops (ELH). Otolin-1 is an otoconial matrix protein that crosses the blood labyrinth barrier and has been found in the serum of healthy and diseased patients.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749390Meniere diseaseotolithic membraneendolymph drainagebiomarkers |
| spellingShingle | Anup Singh Harsha Yadav Hitesh Verma Kapil Sikka Ransi Ann Abraham David Victor Kumar Irugu Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission International Archives of Otorhinolaryngology Meniere disease otolithic membrane endolymph drainage biomarkers |
| title | Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission |
| title_full | Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission |
| title_fullStr | Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission |
| title_full_unstemmed | Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission |
| title_short | Normal Serum Levels of Otolin-1 in Patients with Meniere Disease in Remission |
| title_sort | normal serum levels of otolin 1 in patients with meniere disease in remission |
| topic | Meniere disease otolithic membrane endolymph drainage biomarkers |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1749390 |
| work_keys_str_mv | AT anupsingh normalserumlevelsofotolin1inpatientswithmenierediseaseinremission AT harshayadav normalserumlevelsofotolin1inpatientswithmenierediseaseinremission AT hiteshverma normalserumlevelsofotolin1inpatientswithmenierediseaseinremission AT kapilsikka normalserumlevelsofotolin1inpatientswithmenierediseaseinremission AT ransiannabraham normalserumlevelsofotolin1inpatientswithmenierediseaseinremission AT davidvictorkumarirugu normalserumlevelsofotolin1inpatientswithmenierediseaseinremission |